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Product Details
H00023659-M01
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3B11
Immunogen
LYPLA3 (NP_036452, 314 a.a. approximately 412 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: TEGLVEATMP PGVQLHCLYG TGVPTPDSFY YESFPDRDPK ICFGDGDGTV NLKSALQCQA WQSRQEHQVL LQELPGSEHI EMLANATTLA YLKRVLLGP
Target Information
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene hydrolyzes lysophosphatidylcholine to glycerophosphorylcholine and a free fatty acid. This enzyme is present in the plasma and thought to be associated with high-density lipoprotein. A later paper contradicts the function of this gene. It demonstrates that this gene encodes a lysosomal enzyme instead of a lysophospholipase and has both calcium-independent phospholipase A2 and transacylase activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-O-acylceramide synthase; 1-O-acylceramide synthase {ECO:0000303|PubMed:15294901}; ACS; ACS {ECO:0000303|PubMed:15294901}; group XV phospholipase A2; group XV phospholipase A2 {ECO:0000312|EMBL:AAH98894.1}; LCAT-like lysophospholipase; LCAT-like lysophospholipase {ECO:0000250|UniProtKB:Q8VEB4}; LLPL; LLPL {ECO:0000250|UniProtKB:Q8VEB4}; LPLA2; LPLA2 {ECO:0000303|PubMed:15294901}; Lysophospholipase 3; lysophospholipase 3 (lysosomal phospholipase A2); lysophospholipase 3 {ECO:0000250|UniProtKB:Q8VEB4}; Lysosomal phospholipase A and acyltransferase; Lysosomal phospholipase A2; lysosomal phospholipase A2 {ECO:0000303|PubMed:15294901, ECO:0000312|EMBL:AAS66767.1}; Phospholipase A2 group XV; phospholipase A2, group XV; PLA2G15; pla2g15 {ECO:0000312|Ensembl:ENSRNOP00000026996, ECO:0000312|RGD:1302982}
Gene Aliases: 1-O-acylceramidesynthase; ACS; C87498; GXVPLA2; LLPL; LPLA2; LYPLA3; PLA2G15; UNQ341/PRO540
UniProt ID: (Human) Q8NCC3, (Mouse) Q8VEB4, (Rat) Q675A5
Entrez Gene ID: (Human) 23659, (Mouse) 192654, (Rat) 361401
lysophospholipase activity
phospholipid binding
O-acyltransferase activity
calcium-independent phospholipase A2 activity
dihydrolipoamide branched chain acyltransferase activity
sterol O-acyltransferase activity
N-acetyltransferase activity
palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity
carnitine O-acyltransferase activity
acetyltransferase activity
C-acyltransferase activity
palmitoyltransferase activity
N-acyltransferase activity
acylglycerol O-acyltransferase activity
serine O-acyltransferase activity
O-acetyltransferase activity
O-octanoyltransferase activity
octanoyltransferase activity
O-palmitoyltransferase activity
S-acyltransferase activity
S-acetyltransferase activity
S-malonyltransferase activity
malonyltransferase activity
C-palmitoyltransferase activity
transferase activity
transferase activity, transferring acyl groups
succinyltransferase activity
N-succinyltransferase activity
O-succinyltransferase activity
S-succinyltransferase activity
sinapoyltransferase activity
O-sinapoyltransferase activity
hydrolase activity
peptidyl-lysine N6-myristoyltransferase activity
peptidyl-lysine N6-palmitoyltransferase activity
benzoyl acetate-CoA thiolase activity
3-hydroxybutyryl-CoA thiolase activity
3-ketopimelyl-CoA thiolase activity
N-palmitoyltransferase activity
myristoyltransferase activity
acyl-CoA N-acyltransferase activity
protein-cysteine S-myristoyltransferase activity
protein-cysteine S-acyltransferase activity
dihydrolipoamide S-acyltransferase activity
glucosaminyl-phosphotidylinositol O-acyltransferase activity
ergosterol O-acyltransferase activity
lanosterol O-acyltransferase activity
naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity
2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity
2-methylhexanoyl-CoA C-acetyltransferase activity
butyryl-CoA 2-C-propionyltransferase activity
2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity
L-2-aminoadipate N-acetyltransferase activity
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity
keto acid formate lyase activity
Ras palmitoyltransferase activity
azetidine-2-carboxylic acid acetyltransferase activity
peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
acetyl-CoA:L-lysine N6-acetyltransferase
acyltransferase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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