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产品信息
PA5-72747
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LZTS2 antibody for a 19 amino acid synthetic peptide near the amino terminus of human LZTS2. The immunogen is within amino acids 80 - 130 of LZTS2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718601
靶标信息
LZTS2 is a negative regulator of katanin-mediated microtubule severing and release from the centrosome. LZTS2 is required for central spindle formation and the completion of cytokinesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hLZTS2; Leucine zipper putative tumor suppressor 2; leucine zipper, putative tumor suppressor 2; Protein LAPSER1; putative tumor suppressor LAPSER1; RP11-108L7.8
基因别名: BC014695; KIAA1813; LAPSER1; LZTS2; mKIAA1813
UniProt ID: (Human) Q96JL2, (Mouse) Q91YU6
Entrez Gene ID: (Human) 84445, (Mouse) 226154
cytokinesis
kidney development
mitotic nuclear division
negative regulation of cell proliferation
positive regulation of cell death
Wnt signaling pathway
microtubule severing
nuclear export
spindle midzone assembly
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to nucleus
cell cycle
negative regulation of Wnt signaling pathway
cell division
renal system development
