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产品信息
OSL00023W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from aa region 50-100 of mouse Laforin conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The antigen is homologous in human.
Specificity of this antibody: Laforin.
靶标信息
The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: epilepsy, progressive myoclonus type 2, Lafora disease (laforin); EPM2A; Glucan phosphatase; Glycogen phosphatase; Lafora PTPase; Laforin; LAFPTPase; RP1-28C20.2
基因别名: EPM2; EPM2A; MELF; Tg(TcraK,TcrbK)TG-BFlv; TG-B
UniProt ID: (Human) O95278, (Mouse) Q9WUA5
Entrez Gene ID: (Human) 7957, (Mouse) 13853
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein tyrosine phosphatase activity
protein binding
protein tyrosine/serine/threonine phosphatase activity
protein tyrosine/threonine phosphatase activity
JUN kinase phosphatase activity
phosphohistidine phosphatase activity
inositol bisphosphate phosphatase activity
hydrolase activity
phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
inositol-1,3,4-trisphosphate 4-phosphatase activity
NADP phosphatase activity
transmembrane receptor protein phosphatase activity
carbohydrate phosphatase activity
carbohydrate binding
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
inositol-4,5-bisphosphate 5-phosphatase activity
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol phosphate phosphatase activity
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
inositol-3,4-bisphosphate 4-phosphatase activity
inositol-1,3,4-trisphosphate 1-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity
IDP phosphatase activity
starch binding
