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NeoBiotechnologies
Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) Monoclonal Antibody (LHCGR/7399)
产品信息
3973-MSM9-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2, kappa
分类
Monoclonal
类型
Antibody
克隆号
LHCGR/7399
抗原
Recombinant fragment (around aa 100-300) of human LHCGR protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
Positive Control:HepG2 or Jurkat cells. Human ovarian carcinoma.
Cellular Location: Cytoplasm. Cell surface.
靶标信息
LHCGR encodes the receptor for both luteinizing hormone and choriogonadotropin. It is family 1 of G-protein coupled receptors, FSH/LSH/TSH superfamily, and its basic function is acting as luteinizing hormone/choriogonadotropin receptor (gonadotropin receptor). Regulating the development and function of Leyding cells in males. It also plays a role in male secondary sexual characterdevelopment. Mutations in this gonadotropinreceptor results in disorders of male secondary sexual characteristic development, such as familial male precocious puperty and male pseudohermaphtoditism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HCG receptor; hypergonadotropic hypogonadism; LH/CG-R; LHR; Luteinizing hormone receptor; Lutropin receptor; Lutropin-choriogonadotropic hormone receptor; lutropin/choriogonadotropin receptor
基因别名: HHG; LCGR; LGR2; LH/CG-R; LH/CGR; LHCGR; LHR; LHRHR; LSH-R; ULG5
UniProt ID: (Human) P22888
Entrez Gene ID: (Human) 3973
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
male gonad development
hormone-mediated signaling pathway
ovulation cycle process
male genitalia development
positive regulation of inositol trisphosphate biosynthetic process
luteinizing hormone signaling pathway
positive regulation of cAMP-mediated signaling
cognition
cellular response to gonadotropin stimulus
