Invitrogen

Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), FITC

Ly-6G/Ly-6C Antibody in Flow Cytometry (Flow)

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Ly-6G/Ly-6C Antibody (MA1-10402) in Flow

Separation of murine Ly6G positive cells (red-filled) from murine Ly6G negative cells (black-dashed) in flow cytometry analysis (surface staining) of mouse bone marrow cells stained using anti-mouse Ly6G (RB6-8C5) FITC Monoclonal antibody (Product # MA1-10402) (concentration in sample 0.5 µg/mL).

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产品信息

MA1-10402

应用

建议稀释比

已发表文章

免疫组化 (IHC)

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流式细胞分析 (Flow)

1-4 µg/mL

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其他PubMed (MISC)

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产品规格

种属反应

Mouse

已发表种属

Mouse

宿主/亚型

Rat / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

RB6-8C5

抗原

Murine granulocytes

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偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Size-exclusion chromatography

保存液

PBS, pH 7.4

内含物

15mM sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_11152477

产品详细信息

This antibody detects Ly6G component of Gr-1 antigen, a commonly used surface marker of neutrophils.

靶标信息

Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Inflammatory resolution and vascular barrier restoration after retinal ischemia reperfusion injury.

Journal of neuroinflammation

Abcouwer SF,Shanmugam S,Muthusamy A,Lin CM,Kong D,Hager H,Liu X,Antonetti DA

MA1-10402 was used in Flow Cytometry to suggest that iBRB restoration occurs as TJ complexes are reorganized and that resolution of inflammation and restoration of the iBRB following retinal IR injury are functionally linked.

Thu Aug 26 00:00:00 UTC 2021

Autofluorescence multiphoton microscopy for visualization of tissue morphology and cellular dynamics in murine and human airways.

Laboratory investigation; a journal of technical methods and pathology

Kretschmer S,Pieper M,Hüttmann G,Bölke T,Wollenberg B,Marsh LM,Garn H,König P

MA110402 was used in immunohistochemistry to propose that autofluorescence-based imaging finds previously unknown immune cell interactions in the airway

Mon Aug 01 00:00:00 UTC 2016

Hematopoiesis and stem cell renewal in long-term bone marrow cultures containing catalase.

Blood

Gupta R,Karpatkin S,Basch RS

MA1-10402 was used in flow cytometry to investigate how peroxide affects hematopoiesis

Wed Mar 01 00:00:00 UTC 2006

Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses.

Journal of immunology (Baltimore, Md. : 1950)

Grisaru D,Pick M,Perry C,Sklan EH,Almog R,Goldberg I,Naparstek E,Lessing JB,Soreq H,Deutsch V

MA1-10402 was used in flow cytometry to demonstrate that AChE-R and ARP facilitate granulocytosis

Sun Jan 01 00:00:00 UTC 2006

Mycobacterial dissemination and cellular responses after 1-lobe restricted tuberculosis infection of genetically susceptible and resistant mice.

The Journal of infectious diseases

Mischenko VV,Kapina MA,Eruslanov EB,Kondratieva EV,Lyadova IV,Young DB,Apt AS

MA1-10402 was used in flow cytometry to study mycobacterial dissemination and immune-cell trafficking in tuberculosis

Wed Dec 15 00:00:00 UTC 2004

Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages.

Journal of immunology (Baltimore, Md. : 1950)

Smith P,Walsh CM,Mangan NE,Fallon RE,Sayers JR,McKenzie AN,Fallon PG

MA1-10402 was used in flow cytometry to elucidate how Schistosoma mansoni suppresses T cell activation

Thu Jul 15 00:00:00 UTC 2004

Reduced apoptosis and ameliorated listeriosis in TRAIL-null mice.

Journal of immunology (Baltimore, Md. : 1950)

Zheng SJ,Jiang J,Shen H,Chen YH

MA1-10402 was used in flow cytometry to identify a role for TRAIL in apoptosis during listeriosis

Mon Nov 01 00:00:00 UTC 2004

Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity.

Blood

Melani C,Chiodoni C,Forni G,Colombo MP

MA1-10402 was used in flow cytometry to use the BALB-neuT model to study carcinogenesis.

Mon Sep 15 00:00:00 UTC 2003

Ly-6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon-gamma.

European journal of immunology

Jutila MA,Kroese FG,Jutila KL,Stall AM,Fiering S,Herzenberg LA,Berg EL,Butcher EC

MA1-10402 was used in flow cytometry to use a new Ly-6C-specific antibody to study monocytes, macrophages, and endothelial cells

Tue Nov 01 00:00:00 UTC 1988

Leukocyte-endothelial cell recognition: evidence of a common molecular mechanism shared by neutrophils, lymphocytes, and other leukocytes.

Journal of immunology (Baltimore, Md. : 1950)

Lewinsohn DM,Bargatze RF,Butcher EC

MA1-10402 was used in flow cytometry to show the involvement of the MEL-14 antigen in neutrophil-endothelial cell interactions

Mon Jun 15 00:00:00 UTC 1987

生物信息学

蛋白别名: Granulocyte Marker; Ly-6C1; Ly-6C2; Ly-6G; Ly-6G.1; lymphocyte antigen 6 complex, locus C; lymphocyte antigen 6C precursor (Ly-6C); Lymphocyte antigen 6C1; Lymphocyte antigen 6C2; Lymphocyte antigen 6G; Lymphocyte antigen Ly-6C; lymphocyte differentiation antigen; PML; PMN

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基因别名: AA682074; AA959465; Gr-1; Gr1; Ly-6C; Ly-6C.2; Ly-6C1; Ly-6C2; Ly-6G; Ly6c; Ly6c1; Ly6c2; Ly6g

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UniProt ID: (Mouse) P0CW02, (Mouse) P0CW03, (Mouse) P35461

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Entrez Gene ID: (Mouse) 17067, (Mouse) 100041546, (Mouse) 546644

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