Invitrogen

CD24 Monoclonal Antibody (SN3), FITC

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CD24 Antibody (MA1-10153) in Flow

Separation of human CD24 positive lymphocytes (red-filled) from monocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD24 (SN3) FITC Monoclonal antibody (Product # MA1-10153) using a dilution of 20 µL/100 µL of peripheral whole blood.

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产品信息

MA1-10153

应用

建议稀释比

已发表文章

免疫印迹 (WB)

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免疫组化 (IHC)

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流式细胞分析 (Flow)

20 µL/1x10^6 cells

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

SN3

抗原

Glycoproteins purified from human NALM-1 cell line.

查看免疫原

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

纯化类型

Size-exclusion chromatography

保存液

PBS, pH 7.4, with 0.2% BSA

内含物

15mM sodium azide

保存条件

4° C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

AB_11152641

产品详细信息

This antibody reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.

靶标信息

CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. CD24 is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation, and control of autoimmunity.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Product References

Optimized nonviral gene delivery for primary urinary renal progenitor cells to enhance cell migration.

Journal of biomedical materials research. Part A

Liu GW,Johnson SL,Jain R,Peeler DJ,Shankland SJ,Pun SH

MA1-10153 was used in Flow Cytometry to transfect uRPCs to overexpress CXCR4, an important chemokine receptor that mediates uRPC migration to the kidneys after intravenous injection, and demonstrate that CXCR4-uRPCs exhibit enhanced migration compared to mock-transfected cells.

Sun Dec 01 00:00:00 UTC 2019

CD24 and CD44 in salivary gland pleomorphic adenoma and in human salivary gland morphogenesis: differential markers of glandular structure or stem cell indicators?

Histopathology

Ianez RC,Coutinho-Camillo CM,Buim ME,Pinto CA,Soares FA,Lourenço SV

MA1-10153 was used in immunohistochemistry to study whether CD24 and CD44 expression in salivary glands can be used as markers of cancer stem cells

Sat Jun 01 00:00:00 UTC 2013

CD24 expression as a marker for predicting clinical outcome in human gliomas.

Journal of biomedicine & biotechnology

Deng J,Gao G,Wang L,Wang T,Yu J,Zhao Z

MA1-10153 was used in western blot to study the prognostic value of CD24 expression in human gliomas

Fri Sep 07 00:00:00 UTC 2012

Acetaminophen-induced differentiation of human breast cancer stem cells and inhibition of tumor xenograft growth in mice.

Biochemical pharmacology

Takehara M,Hoshino T,Namba T,Yamakawa N,Mizushima T

MA1-10153 was used in immunohistochemistry to screen compounds able to induce differentiation of cancer stem cells

Sun May 01 00:00:00 UTC 2011

Characterization of sphere-propagating cells with stem-like properties from DU145 prostate cancer cells.

Biochimica et biophysica acta

Rybak AP,He L,Kapoor A,Cutz JC,Tang D

MA1-10153 was used in immunohistochemistry to study sphere-propagating cells with stem-like properties from DU145 prostate cancer cells

Sun May 01 00:00:00 UTC 2011

Association of breast cancer stem cells identified by aldehyde dehydrogenase 1 expression with resistance to sequential Paclitaxel and epirubicin-based chemotherapy for breast cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research

Tanei T,Morimoto K,Shimazu K,Kim SJ,Tanji Y,Taguchi T,Tamaki Y,Noguchi S

MA1-10153 was used in immunohistochemistry to study whether cancer stem cells are clinically significant for resistance to chemotherapy in human breast cancers

Mon Jun 15 00:00:00 UTC 2009

CD24 expression is a novel prognostic factor in esophageal squamous cell carcinoma.

Annals of surgical oncology

Sano A,Kato H,Sakurai S,Sakai M,Tanaka N,Inose T,Saito K,Sohda M,Nakajima M,Nakajima T,Kuwano H

MA1-10153 was used in western blot to study the prognostic value of CD24 overexpression in esophageal squamous cell carcinoma

Sun Feb 01 00:00:00 UTC 2009

The role of extracellular factors in human metastatic chordoma cell growth in vitro.

Spine

Ostroumov E,Hunter CJ

MA1-10153 was used in western blot to study the role of the extracellular microenvironment in human metastatic chordoma cell growth in vitro

Sat Dec 15 00:00:00 UTC 2007

Laser capture microdissection-microarray analysis of focal segmental glomerulosclerosis glomeruli.

Nephron. Experimental nephrology

Bennett MR,Czech KA,Arend LJ,Witte DP,Devarajan P,Potter SS

MA1-10153 was used in immunohistochemistry to analyse the focal segmental glomerulosclerosis glomeruli by laser capture microdissection-microarray method

Tue Oct 02 00:00:00 UTC 2007

CD24 expression is a prognostic factor in intrahepatic cholangiocarcinoma.

Cancer letters

Su MC,Hsu C,Kao HL,Jeng YM

MA1-10153 was used in immunohistochemistry to study CD24 expression as a prognostic factor in intrahepatic cholangiocarcinoma

Sat Apr 08 00:00:00 UTC 2006

Identification and purification of classical Hodgkin cells from lymph nodes by flow cytometry and flow cytometric cell sorting.

American journal of clinical pathology

Fromm JR,Kussick SJ,Wood BL

MA1-10153 was used in flow cytometry to evaluate the use of flow cytometry to identify the Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma

Wed Nov 01 00:00:00 UTC 2006

生物信息学

蛋白别名: CD24; CD24 antigen (small cell lung carcinoma cluster 4 antigen); FLJ22950; FLJ43543; MGC75043; Signal transducer CD24; Small cell lung carcinoma cluster 4 antigen

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基因别名: CD24; CD24A

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UniProt ID: (Human) P25063

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Entrez Gene ID: (Human) 100133941

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功能

signal transducer activity protein binding protein kinase binding protein tyrosine kinase activator activity

参与通路