Product References
High RNA-binding Motif Protein 3 Expression Is Associated with Improved Clinical Outcomes in Invasive Breast Cancer.
Journal of breast cancer
Kang SH,Cho J,Jeong H,Kwon SY
Published figure using Actin monoclonal antibody (Product # MA5-11866) in Western Blot
Sat Sep 01 00:00:00 UTC 2018
Identification of a Novel Human E-Cadherin Splice Variant and Assessment of Its Effects Upon EMT-Related Events.
Journal of cellular physiology
Matos ML,Lapyckyj L,Rosso M,Besso MJ,Mencucci MV,Briggiler CI,Giustina S,Furlong LI,Vazquez-Levin MH
MA511866 was used in western blot to investigate the alternative splicing of E-cadherin mRNA
Thu Jun 01 00:00:00 UTC 2017
A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth.
Disease models & mechanisms
Mayrhofer M,Gourain V,Reischl M,Affaticati P,Jenett A,Joly JS,Benelli M,Demichelis F,Poliani PL,Sieger D,Mione M
MA511866 was used in western blot to propose that neurodevelopmental disorders and brain tumors may arise from changes in oncogenes
Sun Jan 01 00:00:00 UTC 2017
Phospholipase Lpl1 links lipid droplet function with quality control protein degradation.
Molecular biology of the cell
Weisshaar N,Welsch H,Guerra-Moreno A,Hanna J
MA5-11866 was used in western blot to report that Lpl1 as a target of the Rpn4 response
Wed Mar 15 00:00:00 UTC 2017
Anti-infective Activity of 2-Cyano-3-Acrylamide Inhibitors with Improved Drug-Like Properties against Two Intracellular Pathogens.
Antimicrobial agents and chemotherapy
Passalacqua KD,Charbonneau ME,Donato NJ,Showalter HD,Sun D,Wen B,He M,Sun H,O'Riordan MX,Wobus CE
MA511866 was used in western blot to screen for deubiquitinase inhibitors that prevent infection of macrophages by intracellular pathogens
Fri Jul 01 00:00:00 UTC 2016
Increased caveolin-1 in intervertebral disc degeneration facilitates repair.
Arthritis research & therapy
Bach FC,Zhang Y,Miranda-Bedate A,Verdonschot LC,Bergknut N,Creemers LB,Ito K,Sakai D,Chan D,Meij BP,Tryfonidou MA
MA5-11866 was used in western blot to study how the role of increased caveolin-1 can help with repair to intervertebral disc degeneration
Thu Mar 03 00:00:00 UTC 2016
Effect of MUC1/β-catenin interaction on the tumorigenic capacity of pancreatic CD133+ cells.
Oncology letters
Sousa AM,Rei M,Freitas R,Ricardo S,Caffrey T,David L,Almeida R,Hollingsworth MA,Santos-Silva F
MA5-11866 was used in western blot to study CD133+ subpopulations in pancreatic cancer
Thu Sep 01 00:00:00 UTC 2016
Activation of PTHrP-cAMP-CREB1 signaling following p53 loss is essential for osteosarcoma initiation and maintenance.
eLife
Walia MK,Ho PM,Taylor S,Ng AJ,Gupte A,Chalk AM,Zannettino AC,Martin TJ,Walkley CR
MA5-11866 was used in western blot to investigate the PTHrP-cAMP-CREB1 axis in osteosarcoma
Tue Apr 12 00:00:00 UTC 2016
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.
Nature communications
Goossens S,Radaelli E,Blanchet O,Durinck K,Van der Meulen J,Peirs S,Taghon T,Tremblay CS,Costa M,Farhang Ghahremani M,De Medts J,Bartunkova S,Haigh K,Schwab C,Farla N,Pieters T,Matthijssens F,Van Roy N,Best JA,Deswarte K,Bogaert P,Carmichael C,Rickard A,Suryani S,Bracken LS,Alserihi R,Canté-Barrett K,Haenebalcke L,Clappier E,Rondou P,Slowicka K,Huylebroeck D,Goldrath AW,Janzen V,McCormack MP,Lock RB,Curtis DJ,Harrison C,Berx G,Speleman F,Meijerink JP,Soulier J,Van Vlierberghe P,Haigh JJ
MA5-11866 was used in western blot to show that sustained Zeb2 expression initiates T-cell leukemia
Wed Jan 07 00:00:00 UTC 2015
Vaccine-mediated immunotherapy directed against a transcription factor driving the metastatic process.
Cancer research
Ardiani A,Gameiro SR,Palena C,Hamilton DH,Kwilas A,King TH,Schlom J,Hodge JW
MA5-11866 was used in western blot to study the ability of a vaccine targeting the Twist transcription factor to inhibit metastasis in a murine breast tumor model
Tue Apr 01 00:00:00 UTC 2014
WEE1 inhibition alleviates resistance to immune attack of tumor cells undergoing epithelial-mesenchymal transition.
Cancer research
Hamilton DH,Huang B,Fernando RI,Tsang KY,Palena C
MA5-11866 was used in western blot to study inhibition of WEE as a mechanism for overcoming immune resistance during the epithelial-to-mesenchymal transition of tumor cells
Thu May 01 00:00:00 UTC 2014
Poly (ADP-ribose) polymerase inhibitor LT-626: Sensitivity correlates with MRE11 mutations and synergizes with platinums and irinotecan in colorectal cancer cells.
Cancer letters
McPherson LA,Shen Y,Ford JM
MA5-11866 was used in western blot to study the efficacy of a PARP inhibitor in colorectal cancer and the effects of microsatellite instability, MRE11 mutation and co-treatment with platinum compounds or irinotecan
Fri Feb 28 00:00:00 UTC 2014
Virus-encoded ectopic CD74 enhances poxvirus vaccine efficacy.
Immunology
Walline CC,Deffit SN,Wang N,Guindon LM,Crotzer VL,Liu J,Hollister K,Eisenlohr LC,Brutkiewicz RR,Kaplan MH,Blum JS
MA5-11866 was used in western blot to study the improved efficacy of vaccinia virus vaccines ectopically expressing CD74
Tue Apr 01 00:00:00 UTC 2014
Structure-activity relationship in the passage of different pyrrolizidine alkaloids through the gastrointestinal barrier: ABCB1 excretes heliotrine and echimidine.
Molecular nutrition & food research
Hessel S,Gottschalk C,Schumann D,These A,Preiss-Weigert A,Lampen A
MA5-11866 was used in western blot to study the the SAR of pyrrolizidine alkaloids in respect of their passage across the gastrointestinal barrier
Thu May 01 00:00:00 UTC 2014
Inhibition of gamma-secretase activity impedes uterine serous carcinoma growth in a human xenograft model.
Gynecologic oncology
Groeneweg JW,Hall TR,Zhang L,Kim M,Byron VF,Tambouret R,Sathayanrayanan S,Foster R,Rueda BR,Growdon WB
MA5-11866 was used in western blot the study the inhibition of growth of a xenograft model of uterine serous carcinoma following treatment with a gamma-secretase inhibitor
Sun Jun 01 00:00:00 UTC 2014
Prenatal corticosterone and adolescent URB597 administration modulate emotionality and CB1 receptor expression in mice.
Psychopharmacology
Ceci C,Mela V,Macrì S,Marco EM,Viveros MP,Laviola G
MA5-11866 was used in western blot to study the effects of prenatal stress followed by pharmacological enhancement of endocannabinoid signaling in adolescence on murine CB1 receptor expression and emotional responses
Thu May 01 00:00:00 UTC 2014
Active elimination of the marine biotoxin okadaic acid by P-glycoprotein through an in vitro gastrointestinal barrier.
Toxicology letters
Ehlers A,These A,Hessel S,Preiss-Weigert A,Lampen A
MA5-11866 was used in western blot to study the ability of P-glycoprotein to actively eliminate non-cytotoxic concentrations of okadaic acid through an in vitro gastrointestinal barrier
Mon Mar 03 00:00:00 UTC 2014
A phase II study of the EGFR inhibitor gefitinib in patients with acute myeloid leukemia.
Leukemia research
Deangelo DJ,Neuberg D,Amrein PC,Berchuck J,Wadleigh M,Sirulnik LA,Galinsky I,Golub T,Stegmaier K,Stone RM
MA5-11866 was used in western blot to perform a phase II clinical trial of gefitinib in acute myeloid leukemia patients
Tue Apr 01 00:00:00 UTC 2014
Hematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophils.
PloS one
Du Roure C,Versavel A,Doll T,Cao C,Pillonel V,Matthias G,Kaller M,Spetz JF,Kopp P,Kohler H,Müller M,Matthias P
MA5-11866 was used in western blot to study the reduction in circulating eosinophil numbers in response to hematopoietic overexpression of FOG-1 in a transgenic murine model
Thu Jan 15 00:00:00 UTC 2015
Contrasting expression patterns of histone mRNA and microRNA 760 in patients with gastric cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Iwaya T,Fukagawa T,Suzuki Y,Takahashi Y,Sawada G,Ishibashi M,Kurashige J,Sudo T,Tanaka F,Shibata K,Endo F,Katagiri H,Ishida K,Kume K,Nishizuka S,Iinuma H,Wakabayashi G,Mori M,Sasako M,Mimori K
MA5-11866 was used in western blot to study the upregulation of histone mRNA and downregulation of miRNA-760 in gastric cancer patients
Sun Dec 01 00:00:00 UTC 2013
Bone morphogenetic protein 4 promotes mammalian oogonial stem cell differentiation via Smad1/5/8 signaling.
Fertility and sterility
Park ES,Woods DC,Tilly JL
MA5-11866 was used in western blot to study the role of Smad signaling in the mechanism by which BMP-4 induces the differentiation of murine oogonial stem cells
Fri Nov 01 00:00:00 UTC 2013
Organotypic brain slices: a model to study the neurovascular unit micro-environment in epilepsies.
Fluids and barriers of the CNS
Morin-Brureau M,De Bock F,Lerner-Natoli M
MA5-11866 was used in western blot to develop an organotypic brain slice culture as a model to study the role of the neurovascular unit in epilepsy and other neurological disorders
Thu Feb 07 00:00:00 UTC 2013
Multidrug resistance-associated proteins are involved in the transport of the glutathione conjugates of the ultimate carcinogen of benzo[a]pyrene in human Caco-2 cells.
Archives of toxicology
Hessel S,John A,Seidel A,Lampen A
MA5-11866 was used in western blot to study the role of multi-drug resistance proteins in the excretion by Caco-2 cells of gluthathione conjugates of the ultimate carcinogen of benzo[a]pyrene
Fri Feb 01 00:00:00 UTC 2013
Coordinate regulation of N-glycosylation gene DPAGT1, canonical Wnt signaling and E-cadherin adhesion.
Journal of cell science
Sengupta PK,Bouchie MP,Nita-Lazar M,Yang HY,Kukuruzinska MA
MA5-11866 was used in western blot to study the roles of Wnt and E-cadherin in the coordinate regulation of N-glycosylation and DPAGT1 expression
Tue Jan 15 00:00:00 UTC 2013
Galectin-7 and actin are components of amyloid deposit of localized cutaneous amyloidosis.
Experimental dermatology
Miura Y,Harumiya S,Ono K,Fujimoto E,Akiyama M,Fujii N,Kawano H,Wachi H,Tajima S
MA5-11866 was used in western blot to study the presence of galectin-7 and actin in amyloid deposits from localized cutaneous amyloidosis lesions asociated with Bowen's disease
Tue Jan 01 00:00:00 UTC 2013
Senescent human periodontal ligament fibroblasts after replicative exhaustion or ionizing radiation have a decreased capacity towards osteoblastic differentiation.
Biogerontology
Konstantonis D,Papadopoulou A,Makou M,Eliades T,Basdra EK,Kletsas D
MA5-11866 was used in western blot to study the reduced osteoblastic differentiation capability of human peridontal ligament fibroblasts that have become senescent due to replicative exhaustion or ionizing irradiation
Sun Dec 01 00:00:00 UTC 2013
Preference toward a polylysine enantiomer in inhibiting prions.
Amino acids
Jackson KS,Yeom J,Han Y,Bae Y,Ryou C
MA5-11866 was used in western blot to study the relative ability of poly-L-lysine and poly-D-lysine to inhibit prions
Fri Mar 01 00:00:00 UTC 2013
Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status.
The Biochemical journal
Nguyen CH,Lang BJ,Chai RC,Vieusseux JL,Kouspou MM,Price JT
MA5-11866 was used in western blot to study the effects of p53 status on the modulation of clonogenic cellular growth by HSF-1
Sat Jun 01 00:00:00 UTC 2013
Human folliculin delays cell cycle progression through late S and G2/M-phases: effect of phosphorylation and tumor associated mutations.
PloS one
Laviolette LA,Wilson J,Koller J,Neil C,Hulick P,Rejtar T,Karger B,Teh BT,Iliopoulos O
MA5-11866 was used in western blot to study the effects of phosphorylation and cancer-associated mutations on the cell-cycle delaying activity of human folliculin
Thu Apr 17 00:00:00 UTC 2014
Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.
PloS one
Chen XL,Wee NL,Hiong KC,Ong JL,Chng YR,Ching B,Wong WP,Chew SF,Ip YK
MA5-11866 was used in western blot to study the effects of exposure to ammonia on the expression of swamp eel brain Na(+), K(+)-ATPase alpha subunits and the significance for the very high brain ammonia tolerance of this organism
Tue Sep 02 00:00:00 UTC 2014
Proprotein convertase 1/3 (PC1/3) in the rat alveolar macrophage cell line NR8383: localization, trafficking and effects on cytokine secretion.
PloS one
Gagnon H,Refaie S,Gagnon S,Desjardins R,Salzet M,Day R
MA5-11866 was used in western blot to study the expression of proprotein convertase 1/3 in a alveolar macrophage cell line and its role in vessicle trafficking and cytokine secretion
Mon Dec 09 00:00:00 UTC 2013
The uremic toxin adsorbent AST-120 abrogates cardiorenal injury following myocardial infarction.
PloS one
Lekawanvijit S,Kumfu S,Wang BH,Manabe M,Nishijima F,Kelly DJ,Krum H,Kompa AR
MA5-11866 was used in western blot to study the ability of an oral adsorbent of indoxyl sulfate to protect against myocardial infarction-induced cardio-renal injury in a rat model
Mon Sep 29 00:00:00 UTC 2014
Tanshinone IIA increases the bystander effect of herpes simplex virus thymidine kinase/ganciclovir gene therapy via enhanced gap junctional intercellular communication.
PloS one
Xiao J,Zhang G,Qiu P,Liu X,Wu Y,Du B,Li J,Zhou J,Li J,Tan Y
MA5-11866 was used in western blot to study the role of improved intercellular gap junction communication in the mechanism by which tanshinone IIA enhances the bystander effect during HSV-thymidine kinase/ganciclovire gene therapy
Mon Feb 03 00:00:00 UTC 2014
FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies.
Oncotarget
Cipriano R,Miskimen KL,Bryson BL,Foy CR,Bartel CA,Jackson MW
MA5-11866 was used in western blot to study the role of FAM83B as a novel oncogene that interacts with and activates PI3 kinase/Akt and MAPK signaling pathways promoting therapeutic resistance
Wed May 01 00:00:00 UTC 2013
High brain ammonia tolerance and down-regulation of Na+:K+:2Cl(-) Cotransporter 1b mRNA and protein expression in the brain of the Swamp Eel, Monopterus albus, exposed to environmental ammonia or terrestrial conditions.
PloS one
Ip YK,Hou Z,Chen XL,Ong JL,Chng YR,Ching B,Hiong KC,Chew SF
MA5-11866 was used in western blot to study the role of NKCC1 downregulation in the brain of the Swamp eel on exposure to ammonia or terrestrial conditions in the high brain ammonia tolerence of this animal
Mon Apr 28 00:00:00 UTC 2014
Agonist-dependent signaling by group I metabotropic glutamate receptors is regulated by association with lipid domains.
The Journal of biological chemistry
Kumari R,Castillo C,Francesconi A
MA5-11866 was used in western blot to study association of mGluR1 with lipid rafts and the role in modulating agonist-mediated signaling
Fri Nov 01 00:00:00 UTC 2013
Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism.
Cell host & microbe
Backes S,Shapiro JS,Sabin LR,Pham AM,Reyes I,Moss B,Cherry S,tenOever BR
MA5-11866 was used in western blot to study the ability of poxvirus poly(A) polymerase to degrade host microRNAs and the protective effect of microRNA 2'-O-methylation
Thu Aug 16 00:00:00 UTC 2012
Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells.
Cellular and molecular life sciences : CMLS
Le Chalony C,Hoffschir F,Gauthier LR,Gross J,Biard DS,Boussin FD,Pennaneach V
MA5-11866 was used in western blot to study the partial complementation of DNA ligase I deficiency by DNA ligase III in mammalian cells
Sat Sep 01 00:00:00 UTC 2012
Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer.
Oncogene
Jalava SE,Urbanucci A,Latonen L,Waltering KK,Sahu B,Jänne OA,Seppälä J,Lähdesmäki H,Tammela TL,Visakorpi T
MA5-11866 was used in western blot to characterize androgen-regulated microRNAs in castration-resistant prostate cancer
Thu Oct 11 00:00:00 UTC 2012
MicroRNA miR-146a is induced by HTLV-1 tax and increases the growth of HTLV-1-infected T-cells.
International journal of cancer
Tomita M,Tanaka Y,Mori N
MA5-11866 was used in western blot to study the role of miR-146a in the growth of HTLV-1-infected T-cells and the therapeutic significance for adult T-cell leukemia
Tue May 15 00:00:00 UTC 2012
Pharmacologic downregulation of c-FLIP(L) restores juxtacrine death receptor-mediated apoptosis in cancer cells in a peritoneal carcinomatosis model.
International journal of cancer
Shen Y,Herde R,Doxey BW,Xu C,Gray PD,Kuwada SK
MA5-11866 was used in western blot to study the effect of pharmacologically-mediated restoration of death receptor signaling on cancer cell apoptosis and implantation
Sun Apr 01 00:00:00 UTC 2012
Cell movements of the deep layer of non-neural ectoderm underlie complete neural tube closure in Xenopus.
Development (Cambridge, England)
Morita H,Kajiura-Kobayashi H,Takagi C,Yamamoto TS,Nonaka S,Ueno N
MA5-11866 was used in western blot to study the cellular and molecular mechanisms underlying the role of non-neural ectoderm in Xenopus complete neural tube closure
Sun Apr 01 00:00:00 UTC 2012
Advanced glycation end-products induce calpain-mediated degradation of ezrin.
The FEBS journal
McRobert EA,Young AN,Bach LA
MA5-11866 was used in western blot to study the induction of calpain-mediated ezrin proteolysis by advanced glycation endproducts
Sat Sep 01 00:00:00 UTC 2012
Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.
Human molecular genetics
Biswas K,Das R,Eggington JM,Qiao H,North SL,Stauffer S,Burkett SS,Martin BK,Southon E,Sizemore SC,Pruss D,Bowles KR,Roa BB,Hunter N,Tessarollo L,Wenstrup RJ,Byrd RA,Sharan SK
MA5-11866 was used in western blot to study the function of BRCA2 variants using a mouse embryonic stem cell-based assay
Sat Sep 15 00:00:00 UTC 2012
Heat stress induces epithelial plasticity and cell migration independent of heat shock factor 1.
Cell stress & chaperones
Lang BJ,Nguyen L,Nguyen HC,Vieusseux JL,Chai RC,Christophi C,Fifis T,Kouspou MM,Price JT
MA5-11866 was used in western blot to study HSF-1-independent modulation of epithelial cell plasticity and migration by heat stress
Thu Nov 01 00:00:00 UTC 2012
Using soybean trypsin inhibitor as an external loading control for Western blot analysis of tear proteins: application to corneal disease.
Experimental eye research
You J,Hodge C,Wen L,McAvoy JW,Madigan MC,Sutton G
MA5-11866 was used in western blot to study the use of soybean trypsin inhibitor as a loading control for Western blot analysis of tear proteins
Fri Jun 01 00:00:00 UTC 2012
The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1.
Virology
Morandell D,Kaiser A,Herold S,Rostek U,Lechner S,Mitterberger MC,Jansen-Dürr P,Eilers M,Zwerschke W
MA5-11866 was used in western blot to elucidate the gene target of HPV-16 E7 oncoprotein
Fri Jan 20 00:00:00 UTC 2012
PER1 modulates SGLT1 transcription in vitro independent of E-box status.
Digestive diseases and sciences
Balakrishnan A,Stearns AT,Ashley SW,Rhoads DB,Tavakkolizadeh A
MA5-11866 was used in western blot to study the effects of the clock gene PER1 on SGLT1 transcription
Fri Jun 01 00:00:00 UTC 2012
Induction of apoptosis in Eμ-myc lymphoma cells in vitro and in vivo through calpain inhibition.
Experimental hematology
Li H,Nepal RM,Martin A,Berger SA
MA5-11866 was used in western blot to study the ability of calpain inhibition to induce apoptosis in E_-myc lymphoma cells
Sun Jul 01 00:00:00 UTC 2012
Involvement of Rho kinase (ROCK) in sepsis-induced acute lung injury.
Journal of thoracic disease
Cinel I,Ark M,Dellinger P,Karabacak T,Tamer L,Cinel L,Michael P,Hussein S,Parrillo JE,Kumar A,Kumar A
MA5-11866 was used in western blot to studty the effect of a selective Rho kinase inhibitor on sepsis-induced acute lung injury
Wed Feb 01 00:00:00 UTC 2012
Upregulation of heparanase in high-glucose-treated endothelial cells promotes endothelial cell migration and proliferation and correlates with Akt and extracellular-signal-regulated kinase phosphorylation.
Molecular vision
Yuan L,Hu J,Luo Y,Liu Q,Li T,Parish CR,Freeman C,Zhu X,Ma W,Hu X,Yu H,Tang S
MA5-11866 was used in western blot to study the effects of high glucose concentrations on heparanase expression, cell migration and proliferation in human retinal vascular endothelial cells
Tue Nov 13 00:00:00 UTC 2012
Loss of deacetylation activity of Hdac6 affects emotional behavior in mice.
PloS one
Fukada M,Hanai A,Nakayama A,Suzuki T,Miyata N,Rodriguiz RM,Wetsel WC,Yao TP,Kawaguchi Y
MA5-11866 was used in western blot to study the modulation of murine emotional behaviour by HDAC6
Mon Jun 11 00:00:00 UTC 2012
Overexpression of ABCG1 protein attenuates arteriosclerosis and endothelial dysfunction in atherosclerotic rabbits.
Heart international
Münch G,Bültmann A,Li Z,Holthoff HP,Ullrich J,Wagner S,Ungerer M
MA5-11866 was used in immunohistochemistry to study the effects of ABCG1 overexpression in a rabbit model of atherosclerosis
Tue Jun 05 00:00:00 UTC 2012
Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation.
Nature cell biology
Kubota Y,O'Grady P,Saito H,Takekawa M
MA5-11866 was used in western blot to study the mechanism by which oncogenic Ras activates the ERK pathway and promotes carcinogenesis
Tue Mar 01 00:00:00 UTC 2011
A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay.
Blood
Biswas K,Das R,Alter BP,Kuznetsov SG,Stauffer S,North SL,Burkett S,Brody LC,Meyer S,Byrd RA,Sharan SK
MA5-11866 was used in western blot to study the function of Fanconi anemia-associated BRCA2 variants in a murine embryonic stem cell assay
Thu Sep 01 00:00:00 UTC 2011
Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: heparin prevents and treats liver damage.
Hepatology (Baltimore, Md.)
Weerasinghe SV,Moons DS,Altshuler PJ,Shah YM,Omary MB
MA5-11866 was used in western blot to study fibrinogen-gamma proteolysis in apoptotic liver injury in mouse and the potential therapeutic effect of heparin treatment
Fri Apr 01 00:00:00 UTC 2011
Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism
Lin CI,Du J,Shen WT,Whang EE,Donner DB,Griff N,He F,Moore FD,Clark OH,Ruan DT
MA5-11866 was used in western blot to investigate the function of mitogen-inducible gene-6 Mig-6 in papillary thyroid cancer
Tue Mar 01 00:00:00 UTC 2011
ABC50 modulates sensitivity of HL60 leukemic cells to endoplasmic reticulum (ER) stress-induced cell death.
Biochemical pharmacology
Yu Y,Zhang Y,Zhu Z,Berger SA
MA5-11866 was used in western blot to study the role of ABC50 in modulating the sensitivity of HL60 leukemic cells to endoplasmic reticulum stress-induced cell death
Tue Feb 15 00:00:00 UTC 2011
Analysis of the role of IL-21 in development of murine B cell progenitors in the bone marrow.
Journal of immunology (Baltimore, Md. : 1950)
Simard N,Konforte D,Tran AH,Esufali J,Leonard WJ,Paige CJ
MA5-11866 was used in western blot to study the role of IL-21 and IL-21R in the development of murine bone marrow B cell progenitors
Sun May 01 00:00:00 UTC 2011
A DNA-dependent stress response involving DNA-PK occurs in hypoxic cells and contributes to cellular adaptation to hypoxia.
Journal of cell science
Bouquet F,Ousset M,Biard D,Fallone F,Dauvillier S,Frit P,Salles B,Muller C
MA5-11866 was used in western blot to study a DNA-dependent stress response involving DNA-PK in hypoxic cells that contributes to cellular adaptation to hypoxia
Wed Jun 01 00:00:00 UTC 2011
TNF-α-decreased thrombomodulin expression in monocytes is inhibited by propofol through regulation of tristetraprolin and human antigen R activities.
Shock (Augusta, Ga.)
Lin FY,Tsai YT,Lee CY,Lin CY,Lin YW,Li CY,Shih CM,Huang CY,Chang NC,Tsai JC,Chen TL,Tsai CS
MA5-11866 was used in western blot to study the effect of propofol on thrombomodulin expression in TNF-alpha-stimulated monocytes
Thu Sep 01 00:00:00 UTC 2011
Combining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitization.
Biochemical and biophysical research communications
Separovic D,Joseph N,Breen P,Bielawski J,Pierce JS,Buren EV,Bhatti G,Saad ZH,Bai A,Bielawska A
MA5-11866 was used in western blot to study the effects of a combination of photodynamic therapy and LCL85 on sphingolipids and cell death
Fri Jun 10 00:00:00 UTC 2011
Apoptosis-inducing factor contributes to epithelial cell apoptosis induced by enteropathogenic Escherichia coli.
Canadian journal of physiology and pharmacology
Flynn AN,Wang A,McKay DM,Buret AG
MA5-11866 was used in western blot to study the role of AIF in the induction of epithelial cell apoptosis by enteropathogenic Escherichia coli
Tue Feb 01 00:00:00 UTC 2011
Subtype specific elevated expression of hyaluronidase-1 (HYAL-1) in epithelial ovarian cancer.
PloS one
Yoffou PH,Edjekouane L,Meunier L,Tremblay A,Provencher DM,Mes-Masson AM,Carmona E
MA5-11866 was used in western blot to study the expression of hyaluronidase-1 in different sub-types of epithelial ovarian cancer
Wed Nov 02 00:00:00 UTC 2011
A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration.
The Journal of biological chemistry
Boroughs LK,Antonyak MA,Johnson JL,Cerione RA
MA5-11866 was used in western blot to study the role of HSP70 in localizing tissue transglutaminase II to the leading edge of cancer cells and the significance for cancer cell migration
Fri Oct 28 00:00:00 UTC 2011
Effects of EpCAM overexpression on human breast cancer cell lines.
BMC cancer
Gostner JM,Fong D,Wrulich OA,Lehne F,Zitt M,Hermann M,Krobitsch S,Martowicz A,Gastl G,Spizzo G
MA5-11866 was used in western blot to study the effects of EpCAM overexpression on the transcriptome, signaling, and proliferation of human breast cancer cell lines
Mon Jan 31 00:00:00 UTC 2011
A transmembrane protein EIG121L is required for epidermal differentiation during early embryonic development.
The Journal of biological chemistry
Araki T,Kusakabe M,Nishida E
MA5-11866 was used in western blot to study the role of the Xenopus transmembrane protein EIG121L in early embryonic epidermal differentiation
Fri Feb 25 00:00:00 UTC 2011
Disrupting 5-HT(2A) receptor/PDZ protein interactions reduces hyperalgesia and enhances SSRI efficacy in neuropathic pain.
Molecular therapy : the journal of the American Society of Gene Therapy
Pichon X,Wattiez AS,Becamel C,Ehrlich I,Bockaert J,Eschalier A,Marin P,Courteix C
MA5-11866 was used in western blot to study the effect of disrupting interactions bewteen the 5-HT(2A) receptor and PDZ on hyperalgesia and SSRI therapeutic action in diabetic neuropathic pain
Sun Aug 01 00:00:00 UTC 2010
Sulindac reverses aberrant expression and localization of beta-catenin in papillary thyroid cancer cells with the BRAFV600E mutation.
Thyroid : official journal of the American Thyroid Association
Cho NL,Lin CI,Whang EE,Carothers AM,Moore FD,Ruan DT
MA5-11866 was used in western blot to study the effect of nonsteroidal antiinflammatory drug sulindac on beta-catenin in papillary thyroid cancer cells
Tue Jun 01 00:00:00 UTC 2010
Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer.
Molecular cancer research : MCR
Lin CI,Whang EE,Donner DB,Du J,Lorch J,He F,Jiang X,Price BD,Moore FD,Ruan DT
MA5-11866 was used in western blot to evaluate the therapeutic efficacy of autophagy activator RAD001 in the treatment of papillary thyroid cancer
Wed Sep 01 00:00:00 UTC 2010
Plasminogen stimulates propagation of protease-resistant prion protein in vitro.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Mays CE,Ryou C
MA5-11866 was used in western blot to study the role of plasminogen in prion propagation
Wed Dec 01 00:00:00 UTC 2010
Serum cellular apoptosis susceptibility protein is a potential prognostic marker for metastatic colorectal cancer.
The American journal of pathology
Stella Tsai CS,Chen HC,Tung JN,Tsou SS,Tsao TY,Liao CF,Chen YC,Yeh CY,Yeh KT,Jiang MC
MA5-11866 was used in western blot to investigate the prognostic value of serum cellular apoptosis susceptibility protein CSE1L/CAS for metastatic colorectal cancer
Thu Apr 01 00:00:00 UTC 2010
Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2.
Apoptosis : an international journal on programmed cell death
Ark M,Ozdemir A,Polat B
MA5-11866 was used in western blot to study the role of Rho kinases in ouabain-induced human umbilical vein endothelial cell apoptosis
Wed Dec 01 00:00:00 UTC 2010
Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.
Molecular and cellular biology
Deisenroth C,Thorner AR,Enomoto T,Perou CM,Zhang Y
MA5-11866 was used in western blot to study the role of mitochondrial Hep27 in inhibiting Mdm2 and stabilizing p53
Sun Aug 01 00:00:00 UTC 2010
Transactivation of ErbB-2 induced by tumor necrosis factor alpha promotes NF-kappaB activation and breast cancer cell proliferation.
Breast cancer research and treatment
Rivas MA,Tkach M,Beguelin W,Proietti CJ,Rosemblit C,Charreau EH,Elizalde PV,Schillaci R
MA5-11866 was used in western blot to study the role of ErbB2 transactivation in promoting NFkB activation and breast cancer cell proliferation
Thu Jul 01 00:00:00 UTC 2010
Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells.
Experimental cell research
Tai CJ,Shen SC,Lee WR,Liao CF,Deng WP,Chiou HY,Hsieh CI,Tung JN,Chen CS,Chiou JF,Li LT,Lin CY,Hsu CH,Jiang MC
MA5-11866 was used in western blot to report that CSE1L regulates the association of alpha-tubulin with beta-tubulin and promotes migration of MCF-7 breast cancer cells
Fri Oct 15 00:00:00 UTC 2010
Hypoglycosylated E-cadherin promotes the assembly of tight junctions through the recruitment of PP2A to adherens junctions.
Experimental cell research
Nita-Lazar M,Rebustini I,Walker J,Kukuruzinska MA
MA5-11866 was used in western blot to study the mechanism by which hypoglycosylated E-cadherin promotes the formation of tight junctions
Thu Jul 01 00:00:00 UTC 2010
Impaired fear extinction in mice lacking protease nexin-1.
The European journal of neuroscience
Meins M,Herry C,Müller C,Ciocchi S,Moreno E,Lüthi A,Monard D
MA5-11866 was used in western blot to study the effects of protease nexin-1 deletion on auditory fear conditioning
Tue Jun 01 00:00:00 UTC 2010
Activation of Na+/H+ exchanger 1 by neurotensin signaling in pancreatic cancer cell lines.
Biochemical and biophysical research communications
Olszewski U,Hlozek M,Hamilton G
MA5-11866 was used in western blot to investigate the mechanism for cellular pH regulation in response to neurotensin signaling
Fri Mar 12 00:00:00 UTC 2010
N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.
The Journal of biological chemistry
Sengupta PK,Bouchie MP,Kukuruzinska MA
MA5-11866 was used in immunocytochemistry to study the ability of the Wnt/beta-catenin pathway to regulate protein N-glycosylation via modulation of DPAGT-1 expression
Fri Oct 08 00:00:00 UTC 2010
Separating lentiviral vector injection and induction of gene expression in time, does not prevent an immune response to rtTA in rats.
PloS one
Markusic DM,de Waart DR,Seppen J
MA5-11866 was used in western blot to study whether temporal separation of lentiviral vector injection and induction of target protein and rtTA expression reduces the immune response in muscle
Thu Apr 01 00:00:00 UTC 2010
Identification of tetranectin as a potential biomarker for metastatic oral cancer.
International journal of molecular sciences
Arellano-Garcia ME,Li R,Liu X,Xie Y,Yan X,Loo JA,Hu S
MA5-11866 was used in western blot to study the utility of serum or saliva tetranectin as a metastatic oral cancer biomarker
Thu Sep 02 00:00:00 UTC 2010
Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice.
PloS one
Polo ML,Arnoni MV,Riggio M,Wargon V,Lanari C,Novaro V
MA5-11866 was used in western blot to characterize a mouse model of endocrine-resistant breast cancer
Wed May 26 00:00:00 UTC 2010
Epidermal growth factor receptor/beta-catenin/T-cell factor 4/matrix metalloproteinase 1: a new pathway for regulating keratinocyte invasiveness after UVA irradiation.
Cancer research
Jean C,Blanc A,Prade-Houdellier N,Ysebaert L,Hernandez-Pigeon H,Al Saati T,Haure MJ,Coluccia AM,Charveron M,Delabesse E,Laurent G
MA5-11866 was used in western blot to study the role of a novel EGFR/beta-catenin/T-cell factor 4/MMP-1 pathway in regulating keratinocyte invasiveness following UVA irradiation
Wed Apr 15 00:00:00 UTC 2009
Increased expression of androgen receptor sensitizes prostate cancer cells to low levels of androgens.
Cancer research
Waltering KK,Helenius MA,Sahu B,Manni V,Linja MJ,Jänne OA,Visakorpi T
MA5-11866 was used in western blot to study the role of increased expression of androgen receptor in sensitizing prostate cancer cells to low levels of androgens
Thu Oct 15 00:00:00 UTC 2009
Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori.
Proceedings of the National Academy of Sciences of the United States of America
Nossa CW,Jain P,Tamilselvam B,Gupta VR,Chen LF,Schreiber V,Desnoyers S,Blanke SR
MA5-11866 was used in western blot to identify the mechanism of bacterial interference in host cell signaling
Tue Nov 24 00:00:00 UTC 2009
IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas.
Proceedings of the National Academy of Sciences of the United States of America
Moore LM,Holmes KM,Smith SM,Wu Y,Tchougounova E,Uhrbom L,Sawaya R,Bruner JM,Fuller GN,Zhang W
MA5-11866 was used in western blot to investigate the diagnostic and therapeutic value of IGFBP 2 in glioma
Tue Sep 29 00:00:00 UTC 2009
Non-viral Smad7 gene delivery and attenuation of postoperative peritoneal adhesion in an experimental model.
The British journal of surgery
Guo H,Leung JC,Cheung JS,Chan LY,Wu EX,Lai KN
MA5-11866 was used in western blot to study the potential of exogenous Smad7 to prevent fibrogenesis in postoperative peritoneal adhesion
Sun Nov 01 00:00:00 UTC 2009
Roles of neutrophil gelatinase-associated lipocalin in continuous ambulatory peritoneal dialysis-related peritonitis.
Journal of clinical immunology
Leung JC,Lam MF,Tang SC,Chan LY,Tam KY,Yip TP,Lai KN
MA5-11866 was used in western blot to study the role of neutrophil gelatinase-associated lipocalin in peritonitis in peritoneal dialysis patients
Fri May 01 00:00:00 UTC 2009
Anti-inflammatory effects of caffeic acid phenethyl ester (CAPE), a nuclear factor-kappaB inhibitor, on Helicobacter pylori-induced gastritis in Mongolian gerbils.
International journal of cancer
Toyoda T,Tsukamoto T,Takasu S,Shi L,Hirano N,Ban H,Kumagai T,Tatematsu M
MA5-11866 was used in western blot to investigate the influence of nuclear factor-kappaB inhibitor caffeic acid phenethyl ester on the gastritis induced by Helicobacter pylori in Mongolian gerbils
Thu Oct 15 00:00:00 UTC 2009
Diminished intracellular invariant chain expression after vaccinia virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Wang N,Weber E,Blum JS
MA5-11866 was used in western blot to study the mechanism by which vaccinia virus infection decreases intracellular invariant chain expression
Sat Aug 01 00:00:00 UTC 2009
Monitoring of the immunomodulatory effect of CP-690,550 by analysis of the JAK/STAT pathway in kidney transplant patients.
Transplantation
Quaedackers ME,Mol W,Korevaar SS,van Gurp EA,van Ijcken WF,Chan G,Weimar W,Baan CC
MA5-11866 was used in western blot to study the immunomodulatory effects of a small molecule Janus kinase-3 inhibitor in kidney transplant patients by ex vivo measurement of STAT5 phosphoylation status
Tue Oct 27 00:00:00 UTC 2009
Intracellular adaptation of Brucella abortus.
Journal of proteome research
Lamontagne J,Forest A,Marazzo E,Denis F,Butler H,Michaud JF,Boucher L,Pedro I,Villeneuve A,Sitnikov D,Trudel K,Nassif N,Boudjelti D,Tomaki F,Chaves-Olarte E,Guzmán-Verri C,Brunet S,Côté-Martin A,Hunter J,Moreno E,Paramithiotis E
MA5-11866 was used in western blot to study the mechanisms by which Brucella establishes intracellular infections
Sun Mar 01 00:00:00 UTC 2009
EHD3 regulates early-endosome-to-Golgi transport and preserves Golgi morphology.
Journal of cell science
Naslavsky N,McKenzie J,Altan-Bonnet N,Sheff D,Caplan S
MA5-11866 was used in western blot to study the role of EHD3 in the regulation of endosome-to-Golgi transport
Sun Feb 01 00:00:00 UTC 2009
The transcription-independent mitochondrial p53 program is a major contributor to nutlin-induced apoptosis in tumor cells.
Cell cycle (Georgetown, Tex.)
Vaseva AV,Marchenko ND,Moll UM
MA5-11866 was used in western blot to study the role of the transcription-independent mitochondrial p53 program in nutlin-induced apoptosis in tumor cells
Mon Jun 01 00:00:00 UTC 2009
SDF-1 alpha expression during wound healing in the aged is HIF dependent.
Plastic and reconstructive surgery
Loh SA,Chang EI,Galvez MG,Thangarajah H,El-Ftesi S,Vial IN,Lin DA,Gurtner GC
MA5-11866 was used in western blot to study the role of IL-1 beta and HIF-1 alpha in SDF-1 alpha expression during wound healing in aged mice
Sun Feb 01 00:00:00 UTC 2009
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
Human molecular genetics
Kim M,Suh J,Romano D,Truong MH,Mullin K,Hooli B,Norton D,Tesco G,Elliott K,Wagner SL,Moir RD,Becker KD,Tanzi RE
MA5-11866 was used in western blot to study the effect on alpha secretase activity of two ADAM10 mutations associated with late-onset Alzheimer's disease
Thu Oct 15 00:00:00 UTC 2009
Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth.
Molecular and cellular biology
Proietti CJ,Rosemblit C,Beguelin W,Rivas MA,Díaz Flaqué MC,Charreau EH,Schillaci R,Elizalde PV
MA5-11866 was used in western blot to investigate the role of Stat3 in the tumorigenic effect of heregulin/ErbB-2 in breast cells
Sun Mar 01 00:00:00 UTC 2009
Proteomic approach to ETV5 during endometrial carcinoma invasion reveals a link to oxidative stress.
Carcinogenesis
Monge M,Colas E,Doll A,Gil-Moreno A,Castellvi J,Diaz B,Gonzalez M,Lopez-Lopez R,Xercavins J,Carreras R,Alameda F,Canals F,Gabrielli F,Reventos J,Abal M
MA5-11866 was used in western blot to study the proteomics of the ETV5 transcription factor during endometrial carcinoma invasion
Sat Aug 01 00:00:00 UTC 2009
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity.
DNA repair
Tate CM,Fishel ML,Holleran JL,Egorin MJ,Skalnik DG
MA5-11866 was used in western blot to study the hypersensitivity to DNA-damaging agents of embryonic stem cells lacking the epigenetic regulator Cfp1
Thu Dec 03 00:00:00 UTC 2009
Autophagy: a new target for advanced papillary thyroid cancer therapy.
Surgery
Lin CI,Whang EE,Abramson MA,Jiang X,Price BD,Donner DB,Moore FD,Ruan DT
MA5-11866 was used in western blot to investigate the therapeutic benefit of autophagy inhibition in the tretment of advanced papillary thyroid cancer
Tue Dec 01 00:00:00 UTC 2009
Clustering of fibroblasts induces proinflammatory chemokine secretion promoting leukocyte migration.
Molecular immunology
Enzerink A,Salmenperä P,Kankuri E,Vaheri A
MA5-11866 was used in western blot to study the role of fibroblast clustering in inducing proinflammatory chemokine secretion and leukocyte migration
Fri May 01 00:00:00 UTC 2009
Short and long-term tumor cell responses to Aurora kinase inhibitors.
Experimental cell research
Dreier MR,Grabovich AZ,Katusin JD,Taylor WR
MA5-11866 was used in western blot to study tumor cell responses to Aurora kinase inhibitors
Wed Apr 15 00:00:00 UTC 2009
Higher prevalence of secretory CSE1L/CAS in sera of patients with metastatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tung MC,Tsai CS,Tung JN,Tsao TY,Chen HC,Yeh KT,Liao CF,Jiang MC
MA5-11866 was used in western blot to evaluate the secretory CSE1L/CAS as a diagnostic marker in cancer metastasis
Fri May 01 00:00:00 UTC 2009
p53-dependent antiproliferative and antitumor effect of novel alkyl series of diorganotin(IV) compounds.
Investigational new drugs
Koch B,Basu Baul TS,Chatterjee A
MA5-11866 was used in western blot to investigate the effect of diorganotin dichloride complexes on tumor growth
Sat Aug 01 00:00:00 UTC 2009
Galectin-3 regulates apoptosis and doxorubicin chemoresistance in papillary thyroid cancer cells.
Biochemical and biophysical research communications
Lin CI,Whang EE,Abramson MA,Donner DB,Bertagnolli MM,Moore FD,Ruan DT
MA5-11866 was used in western blot to investigate the influence of galectin-3 on cell survival and drug resistance in PTC cells
Fri Feb 06 00:00:00 UTC 2009
Puerariae radix isoflavones and their metabolites inhibit growth and induce apoptosis in breast cancer cells.
Biochemical and biophysical research communications
Lin YJ,Hou YC,Lin CH,Hsu YA,Sheu JJ,Lai CH,Chen BH,Lee Chao PD,Wan L,Tsai FJ
MA5-11866 was used in western blot to study the effect of Puerariae radix isoflavones on growth and apoptosis in breast cancer cells
Fri Jan 23 00:00:00 UTC 2009
Classic and desmoplastic medulloblastoma: complete case reports and characterizations of two new cell lines.
Neuropathology : official journal of the Japanese Society of Neuropathology
Holthouse DJ,Dallas PB,Ford J,Fabian V,Murch AR,Watson M,Wong G,Bertram C,Egli S,Baker DL,Kees UR
MA5-11866 was used in western blot to report on two cases of classic and desmoplastic medulloblastoma and the characterization of two new cell lines
Sat Aug 01 00:00:00 UTC 2009
Increased renal gene transcription of protein kinase C-beta in human diabetic nephropathy: relationship to long-term glycaemic control.
Diabetologia
Langham RG,Kelly DJ,Gow RM,Zhang Y,Cox AJ,Qi W,Thai K,Pollock CA,Christensen PK,Parving HH,Gilbert RE
MA5-11866 was used in western blot to study whether diabetic nephropathy leads to increased transcription of PKC-alpha and PKC-beta
Tue Apr 01 00:00:00 UTC 2008
Dulxanthone A induces cell cycle arrest and apoptosis via up-regulation of p53 through mitochondrial pathway in HepG2 cells.
International journal of cancer
Tian Z,Shen J,Moseman AP,Yang Q,Yang J,Xiao P,Wu E,Kohane IS
MA5-11866 was used in western blot to study the mechanism by which dulxanthone A induces cell cycle arrest and apoptosis in HepG2 cells
Tue Jan 01 00:00:00 UTC 2008
Synthesis of TNF-alpha by mesangial cells cultured with polymeric anionic IgA--role of MAPK and NF-kappaB.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Leung JC,Tang SC,Chan LY,Chan WL,Lai KN
MA5-11866 was used in western blot to study the role of MAPK and NFkB in the synthesis of TNFalpha by mesangial cells cultured with polymeric anionic IgA
Tue Jan 01 00:00:00 UTC 2008
Phosphorylated Ssk1 prevents unphosphorylated Ssk1 from activating the Ssk2 mitogen-activated protein kinase kinase kinase in the yeast high-osmolarity glycerol osmoregulatory pathway.
Molecular and cellular biology
Horie T,Tatebayashi K,Yamada R,Saito H
MA5-11866 was used in western blot to study the role of Ssk1 phosphorylation status in regulating the activation of the Ssk2 MAPK kinase kinase involved in yeast osmoregulation
Mon Sep 01 00:00:00 UTC 2008
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally.
Molecular and cellular biology
Zhang Y,Kwon S,Yamaguchi T,Cubizolles F,Rousseaux S,Kneissel M,Cao C,Li N,Cheng HL,Chua K,Lombard D,Mizeracki A,Matthias G,Alt FW,Khochbin S,Matthias P
MA5-11866 was used in western blot to study the characteristics of knockout mice lacking HDAC6
Sat Mar 01 00:00:00 UTC 2008
Mammalian hyaluronidase induces ovarian granulosa cell apoptosis and is involved in follicular atresia.
Endocrinology
Orimoto AM,Dumaresq-Doiron K,Jiang JY,Tanphaichitr N,Tsang BK,Carmona E
MA5-11866 was used in western blot to study the possible involvement of mammalian hyaluronidases in ovarian atresia
Sat Nov 01 00:00:00 UTC 2008
Hepatocyte growth factor improves viability after H2O2-induced toxicity in bile duct epithelial cells.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
Arends B,Slump E,Spee B,Rothuizen J,Penning LC
MA5-11866 was used in western blot to study the effect of HGF on the viability of bile duct epithelial cells following H2O2-induced toxicity
Tue Apr 01 00:00:00 UTC 2008
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth.
DNA repair
Fishel ML,He Y,Reed AM,Chin-Sinex H,Hutchins GD,Mendonca MS,Kelley MR
MA5-11866 was used in western blot to study the role of the DNA repair and redox signaling protein Ape1/Ref-1 in ovarian cancer cell and tumor growth
Fri Feb 01 00:00:00 UTC 2008
NBS1 regulates a novel apoptotic pathway through Bax activation.
DNA repair
Iijima K,Muranaka C,Kobayashi J,Sakamoto S,Komatsu K,Matsuura S,Kubota N,Tauchi H
MA5-11866 was used in western blot to study the regulation of a novel p53-independent apoptotic pathway
Wed Oct 01 00:00:00 UTC 2008
Diurnal rhythmicity in glucose uptake is mediated by temporal periodicity in the expression of the sodium-glucose cotransporter (SGLT1).
Surgery
Balakrishnan A,Stearns AT,Rounds J,Irani J,Giuffrida M,Rhoads DB,Ashley SW,Tavakkolizadeh A
MA5-11866 was used in western blot to study temporal changes in glucose transport mediated by the Na(+)/glucose cotransporter SGLT1
Sun Jun 01 00:00:00 UTC 2008
Cell proliferation inhibition and antitumor activity of novel alkyl series of diorganotin(IV) compounds.
Journal of applied toxicology : JAT
Koch B,Baul TS,Chatterjee A
MA5-11866 was used in western blot to investigate the effect of diorganotin compounds on cell proliferation and tumor growth
Thu May 01 00:00:00 UTC 2008
CRBL cells: establishment, characterization and susceptibility to prion infection.
Brain research
Mays CE,Kang HE,Kim Y,Shim SH,Bang JE,Woo HJ,Cho YH,Kim JB,Ryou C
MA5-11866 was used in western blot to characterize a new immortal cell lines for the study of prion pathogenesis
Wed May 07 00:00:00 UTC 2008
Effect of hemodialysis on hepatic cytochrome P450 functional expression.
Journal of pharmacological sciences
Michaud J,Nolin TD,Naud J,Dani M,Lafrance JP,Leblond FA,Himmelfarb J,Pichette V
MA5-11866 was used in western blot to study the functional expression of CYP1A, 2C, and 3A during conventional hemodialysis
Wed Oct 01 00:00:00 UTC 2008
Oocyte selection is concurrent with meiosis resumption in the coenocystic oogenesis of Oikopleura.
Developmental biology
Ganot P,Moosmann-Schulmeister A,Thompson EM
MA5-11866 was used in immunohistochemistry and western blot to study the growth and maturation of oocytes in the tunicate Oikopleura
Mon Dec 15 00:00:00 UTC 2008
Oocyte selection is concurrent with meiosis resumption in the coenocystic oogenesis of Oikopleura.
Developmental biology
Ganot P,Moosmann-Schulmeister A,Thompson EM
MA5-11866 was used in immunohistochemistry and western blot to study the growth and maturation of oocytes in the tunicate Oikopleura
Mon Dec 15 00:00:00 UTC 2008
Lithium treatment decreases activities of tau kinases in a murine model of senescence.
Journal of neuropathology and experimental neurology
Tajes M,Gutierrez-Cuesta J,Folch J,Ferrer I,Caballero B,Smith MA,Casadesus G,Camins A,Pallás M
MA5-11866 was used in western blot to study the effect of lithium on the acctivity of tau kinases in a mouse model of senescence
Sun Jun 01 00:00:00 UTC 2008
Exercise training with dietary counselling increases mitochondrial chaperone expression in middle-aged subjects with impaired glucose tolerance.
BMC endocrine disorders
Venojärvi M,Aunola S,Puhke R,Marniemi J,Hämäläinen H,Halonen JP,Lindström J,Rastas M,Hällsten K,Nuutila P,Hänninen O,Atalay M
MA5-11866 was used in western blot to study the effects of exercise and diet on mitochondrial chaperone expression in obese middle-aged subjects suffereing impaired glucose tolerance
Thu Mar 27 00:00:00 UTC 2008
Differential transferrin expression in placentae from normal and abnormal pregnancies: a pilot study.
Reproductive biology and endocrinology : RB&E
Kralova A,Svetlikova M,Madar J,Ulcova-Gallova Z,Bukovsky A,Peknicova J
MA5-11866 was used in western blot to compare placental transferrin expression following normal or abnormal pregnancies
Wed Jul 02 00:00:00 UTC 2008
In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis.
The Journal of biological chemistry
Surucu B,Bozulic L,Hynx D,Parcellier A,Hemmings BA
MA5-11866 was used in western blot to study the role of PKB/Akt in the DNA damage response and tumorigenesis using DNA-PKcs knockout mice
Fri Oct 31 00:00:00 UTC 2008
Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.
The Journal of biological chemistry
Tsao PN,Chen F,Izvolsky KI,Walker J,Kukuruzinska MA,Lu J,Cardoso WV
MA5-11866 was used in western blot to study the role of gamma-secretase activation of Notch signaling in regulating the fates of progenitor cells in the developing lung
Fri Oct 24 00:00:00 UTC 2008
Positive regulation of DNA double strand break repair activity during differentiation of long life span cells: the example of adipogenesis.
PloS one
Meulle A,Salles B,Daviaud D,Valet P,Muller C
MA5-11866 was used in western blot to study the reugulation of DNA double strand break repair activity during adipocyte differentiation
Wed Nov 12 00:00:00 UTC 2008
Identification of a hepatitis B virus S gene mutant in lamivudine-treated patients experiencing HBsAg seroclearance.
Gastroenterology
Hsu CW,Yeh CT,Chang ML,Liaw YF
MA5-11866 was used in western blot to study the mechanism and significance of HBsAg seroclearance in HBV patients treated with lamivudine
Thu Feb 01 00:00:00 UTC 2007
Smad7 transgene attenuates peritoneal fibrosis in uremic rats treated with peritoneal dialysis.
Journal of the American Society of Nephrology : JASN
Guo H,Leung JC,Lam MF,Chan LY,Tsang AW,Lan HY,Lai KN
MA5-11866 was used in western blot to study the role of the Smad7 transgene in reducing peritoneal fibrosis in uremic rats undergoing peritoneal dialysis
Mon Oct 01 00:00:00 UTC 2007
Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis.
Cancer research
Takami T,Kaposi-Novak P,Uchida K,Gomez-Quiroz LE,Conner EA,Factor VM,Thorgeirsson SS
MA5-11866 was used in western blot to investigate the effect of c-Met signaling deficiency in hepatocytes on chemical hepatocarcinogenesis
Mon Oct 15 00:00:00 UTC 2007
Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
PLoS medicine
Stegmaier K,Wong JS,Ross KN,Chow KT,Peck D,Wright RD,Lessnick SL,Kung AL,Golub TR
MA5-11866 was used in western blot to develop a novel method for screening for small molecule modulators of EWS/FLI oncoprotein function in Ewing sarcoma
Sun Apr 01 00:00:00 UTC 2007
The ubiquitin-proteasome system regulates p53-mediated transcription at p21waf1 promoter.
Oncogene
Zhu Q,Wani G,Yao J,Patnaik S,Wang QE,El-Mahdy MA,Praetorius-Ibba M,Wani AA
MA5-11866 was used in western blot to study the role of the ubiquitin-proteasome system in the transcriptional activation function of p53
Thu Jun 21 00:00:00 UTC 2007
Carvedilol, a pharmacological antioxidant, inhibits neointimal matrix metalloproteinase-2 and -9 in experimental atherosclerosis.
Free radical biology & medicine
Wu TC,Chen YH,Leu HB,Chen YL,Lin FY,Lin SJ,Chen JW
MA5-11866 was used in western blot to study the effects of carvedilol on MMP-2 and MMP-9 expression in experimental atherosclerosis
Sat Dec 01 00:00:00 UTC 2007
Sodium butyrate-induced death-associated protein kinase expression promote Raji cell morphological change and apoptosis by reducing FAK protein levels.
Acta pharmacologica Sinica
Zhang HT,Feng ZL,Wu J,Wang YJ,Guo X,Liang NC,Zhu ZY,Ma JQ
MA5-11866 was used in western blot to investigate the mechanism for the effect of death-associated protein kinase on Raji cell morphology and survival
Thu Nov 01 00:00:00 UTC 2007
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma.
Molecular cancer therapeutics
Frederick BA,Helfrich BA,Coldren CD,Zheng D,Chan D,Bunn PA,Raben D
MA5-11866 was used in western blot to investigate the mechanism for the gefitinib resistance in head and neck squamous cell carcinoma and non-small cell lung carcinoma
Fri Jun 01 00:00:00 UTC 2007
Cimicifuga foetida extract inhibits proliferation of hepatocellular cells via induction of cell cycle arrest and apoptosis.
Journal of ethnopharmacology
Tian Z,Pan R,Chang Q,Si J,Xiao P,Wu E
MA5-11866 was used in western blot to study the mechanism by which an extract of Cimicifuga foetida inhibits proliferation of hepatocellular cells
Thu Nov 01 00:00:00 UTC 2007
Prolactin stimulates prostate cell proliferation by increasing endoplasmic reticulum content due to SERCA 2b over-expression.
The Biochemical journal
Crépin A,Bidaux G,Vanden-Abeele F,Dewailly E,Goffin V,Prevarskaya N,Slomianny C
MA5-11866 was used in western blot to study the role of SERCA2b overexpression and endoplasmic calcium metabolism in the stimulation of prostate cell growth by prolactin
Mon Jan 01 00:00:00 UTC 2007
Coincident regulation of PKCdelta in human platelets by phosphorylation of Tyr311 and Tyr565 and phospholipase C signalling.
The Biochemical journal
Hall KJ,Jones ML,Poole AW
MA5-11866 was used in western blot to study the co-regulation of PKCdelta in human platelets by phosphorylation of Tyr311 and Tyr565 and phospholipase C signalling
Sat Sep 15 00:00:00 UTC 2007
Heavy ion beams induce survivin expression in human hepatoma SMMC-7721 cells more effectively than X-rays.
Acta biochimica et biophysica Sinica
Gong L,Jin X,Li Q,Liu J,An L
MA5-11866 was used in western blot to compare the ability of heavy ion beams and X-rays to induce survivin expression in human hepatoma cells
Wed Aug 01 00:00:00 UTC 2007
Influence of glutathione on the induction of chromosome aberrations, delay in cell cycle kinetics and cell cycle regulator proteins in irradiated mouse bone marrow cells.
International journal of radiation biology
Ray S,Chatterjee A
MA5-11866 was used in western blot to investigate the effect of glutathione on chromosome aberrations, cell cycle kinetics, and cell cycle regulator proteins
Tue May 01 00:00:00 UTC 2007
Inhibition of NAD(P)H oxidase reduces fibronectin expression in stroke-prone renovascular hypertensive rat brain.
Clinical and experimental pharmacology & physiology
Cui C,Chen AF,Jiang Z,Wu Q,Lin J,Wen H,Zeng J
MA5-11866 was used in western blot to study the role of NAD(H) oxidase inhibition in reducing fibronectin expression in a hypertensive stroke model
Sun Apr 01 00:00:00 UTC 2007
Effect of huanglian jiedu decoction ) on glucose transporter 4 expression in adipose and skeletal muscle tissues of insulin resistant rats.
Chinese journal of integrative medicine
Chen G,Lu FE,Jin D,Xu LJ,Wang KF
MA5-11866 was used in western blot to study the effect of huanglian jiedu decoction on glucose transporter 4 expression in adipose and skeletal muscle tissues of insulin resistant rats
Thu Mar 01 00:00:00 UTC 2007
P53-Rb signaling pathway is involved in tubular cell senescence in renal ischemia/reperfusion injury.
Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al
Kailong L,Du X,Yani H,Lin Z,Jvrong Y,Ruihua S,Lin C
MA5-11866 was used in western blot to investigate the involvement of p53-Rb signaling pathway in tubular cell senescence in the kidney during the late phase of ischemia/reperfusion
Wed Aug 01 00:00:00 UTC 2007
UVA induces granzyme B in human keratinocytes through MIF: implication in extracellular matrix remodeling.
The Journal of biological chemistry
Hernandez-Pigeon H,Jean C,Charruyer A,Haure MJ,Baudouin C,Charveron M,Quillet-Mary A,Laurent G
MA5-11866 was used in western blot to study the role of MIF in UVA induced-granzyme B expression in human keratinocytes
Fri Mar 16 00:00:00 UTC 2007
Analysis of mitotic phosphorylation of borealin.
BMC cell biology
Kaur H,Stiff AC,Date DA,Taylor WR
MA5-11866 was used in western blot to study the phosphorylation of borealin during mitosis
Mon Jan 22 00:00:00 UTC 2007
Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families.
The Journal of biological chemistry
Kim M,Hersh LB,Leissring MA,Ingelsson M,Matsui T,Farris W,Lu A,Hyman BT,Selkoe DJ,Bertram L,Tanzi RE
MA5-11866 was used in western blot to study decreased catalytic activity of insulin-degrading enzyme in chromosome 10-linked Alzheimer disease
Fri Mar 16 00:00:00 UTC 2007
Efficient intervention of growth and infiltration of primary adult T-cell leukemia cells by an HIV protease inhibitor, ritonavir.
Blood
Dewan MZ,Uchihara JN,Terashima K,Honda M,Sata T,Ito M,Fujii N,Uozumi K,Tsukasaki K,Tomonaga M,Kubuki Y,Okayama A,Toi M,Mori N,Yamamoto N
MA5-11866 was used in western blot to study the effect of the HIV protease inhibitor ritonavir on the growth and infiltration of HTLV-I-infected T-cell lines and primary adult T-cell leukemia cells
Sun Jan 15 00:00:00 UTC 2006
Leptin induces TGF-beta synthesis through functional leptin receptor expressed by human peritoneal mesothelial cell.
Kidney international
Leung JC,Chan LY,Tang SC,Chu KM,Lai KN
MA5-11866 was used in western blot to study whether human peritoneal mesothelial cells express functional leptin receptor and the possible significance for peritoneal dialysis
Thu Jun 01 00:00:00 UTC 2006
Improved surgical mesh integration into the rat abdominal wall with arginine administration.
Biomaterials
Arbos MA,Ferrando JM,Quiles MT,Vidal J,López-Cano M,Gil J,Manero JM,Peña J,Huguet P,Schwartz-Riera S,Reventós J,Armengol M
MA5-11866 was used in western blot to study the role of arginine administration in improving surgical mesh integration into the rat abdominal wall
Wed Feb 01 00:00:00 UTC 2006
Role of parathyroid hormone in the downregulation of liver cytochrome P450 in chronic renal failure.
Journal of the American Society of Nephrology : JASN
Michaud J,Naud J,Chouinard J,Désy F,Leblond FA,Desbiens K,Bonnardeaux A,Pichette V
MA5-11866 was used in western blot to study the role parathyroid hormone in the downregulation of liver cytochrome P450 in chronic renal failure
Wed Nov 01 00:00:00 UTC 2006
Lineage-specific activators affect beta-globin locus chromatin in multipotent hematopoietic progenitors.
The EMBO journal
Bottardi S,Ross J,Pierre-Charles N,Blank V,Milot E
MA5-11866 was used in western blot to study the effect of lineage-specific activators on beta-globin locus chromatin in multipotent hematopoietic progenitors
Wed Aug 09 00:00:00 UTC 2006
Mutations within the kinase domain and truncations of the epidermal growth factor receptor are rare events in bladder cancer: implications for therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Blehm KN,Spiess PE,Bondaruk JE,Dujka ME,Villares GJ,Zhao YJ,Bogler O,Aldape KD,Grossman HB,Adam L,McConkey DJ,Czerniak BA,Dinney CP,Bar-Eli M
MA5-11866 was used in western blot to study the therapeutic implications of mutations and truncations of the EGF receptor in bladder cancer
Tue Aug 01 00:00:00 UTC 2006
Altered glucose metabolism in childhood pre-B acute lymphoblastic leukaemia.
Leukemia
Boag JM,Beesley AH,Firth MJ,Freitas JR,Ford J,Hoffmann K,Cummings AJ,de Klerk NH,Kees UR
MA5-11866 was used in western blot to study glucose metabolism in childhood pre-B acute lymphoblastic leukaemia
Sun Oct 01 00:00:00 UTC 2006
Two isoforms of tissue transglutaminase mediate opposing cellular fates.
Proceedings of the National Academy of Sciences of the United States of America
Antonyak MA,Jansen JM,Miller AM,Ly TK,Endo M,Cerione RA
MA5-11866 was used in western blot to study the opposing effects on cell fate of two alternative tissue transglutaminase transcripts
Tue Dec 05 00:00:00 UTC 2006
Stress response in mesoangioblast stem cells.
Cell death and differentiation
Geraci F,Turturici G,Galli D,Cossu G,Giudice G,Sconzo G
MA5-11866 was used in western blot to study the ability of mesoangioblasts to respond to different cell stresses
Sat Jul 01 00:00:00 UTC 2006
Progestin-induced caveolin-1 expression mediates breast cancer cell proliferation.
Oncogene
Salatino M,Beguelin W,Peters MG,Carnevale R,Proietti CJ,Galigniana MD,Vedoy CG,Schillaci R,Charreau EH,Sogayar MC,Elizalde PV
MA5-11866 was used in western blot to investigate the role of caveolin-1 in breast cancer cell proliferation
Thu Dec 14 00:00:00 UTC 2006
The topoisomerase II-Hsp90 complex: a new chemotherapeutic target?
International journal of cancer
Barker CR,Hamlett J,Pennington SR,Burrows F,Lundgren K,Lough R,Watson AJ,Jenkins JR
MA5-11866 was used in immunoprecipitation and western blot to study the topoisomerase II-Hsp90 complex as a potential new chemotherapeutic target
Thu Jun 01 00:00:00 UTC 2006
Proteomic analysis of Caco-2 cells treated with monacolin K.
Journal of agricultural and food chemistry
Lin WY,Song CY,Pan TM
MA5-11866 was used in western blot to perform a proteomic analysis of Caco-2 cells treated with monacolin K
Wed Aug 23 00:00:00 UTC 2006
Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway.
Journal of immunology (Baltimore, Md. : 1950)
Schillaci R,Salatino M,Cassataro J,Proietti CJ,Giambartolomei GH,Rivas MA,Carnevale RP,Charreau EH,Elizalde PV
MA5-11866 was used in western blot to study the anti-tumor effects of anti-sense oligonucleotides to IGF-1R in murine breast cancer
Wed Mar 15 00:00:00 UTC 2006
Evidence for a role for notch signaling in the cytokine-dependent survival of activated T cells.
Journal of immunology (Baltimore, Md. : 1950)
Bheeshmachar G,Purushotaman D,Sade H,Gunasekharan V,Rangarajan A,Sarin A
MA5-11866 was used in western blot to study the potential role of Notch1 signaling in cytokine-dependent survival of activated T cells
Sun Oct 15 00:00:00 UTC 2006
PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts.
Journal of cell science
Baudry A,Yang ZZ,Hemmings BA
MA5-11866 was used in western blot to study the role of PKBalpha in the adipose differentiation of murine embryonic stem cells
Wed Mar 01 00:00:00 UTC 2006
Inhibition of K+ efflux prevents mitochondrial dysfunction, and suppresses caspase-3-, apoptosis-inducing factor-, and endonuclease G-mediated constitutive apoptosis in human neutrophils.
Cellular signalling
El Kebir D,József L,Khreiss T,Filep JG
MA5-11866 was used in western blot to study whether prevention of K(+) efflux could affect the apoptotic machinery in human neutrophils
Fri Dec 01 00:00:00 UTC 2006
Stellettin A induces oxidative stress and apoptosis in HL-60 human leukemia and LNCaP prostate cancer cell lines.
Journal of natural products
Liu WK,Cheung FW,Che CT
MA5-11866 was used in western blot to investigate the effect of stellettin A on oxidative cell death
Thu Jun 01 00:00:00 UTC 2006
Overexpression of EIF3S3 promotes cancer cell growth.
The Prostate
Savinainen KJ,Helenius MA,Lehtonen HJ,Visakorpi T
MA5-11866 was used in western blot to investigate the impact of EIF3S3 on cancer cell growth
Tue Aug 01 00:00:00 UTC 2006
Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability.
Molecular biology of the cell
Gavarini S,Bécamel C,Altier C,Lory P,Poncet J,Wijnholds J,Bockaert J,Marin P
MA5-11866 was used in western blot to study the effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine-2C receptor desensitization and membrane stability
Wed Nov 01 00:00:00 UTC 2006
A comparison of enhanced green fluorescent protein expression induced by immediate-early cytomegalovirus (IE-CMV) and gG pseudorabies virus (gG-PRV) promoters, using pseudorabies virus amplicons as vectors.
Journal of virological methods
Muñoz AL,Prieto C,Tabarés E
MA5-11866 was used in western blot to study the expression efficiencies of the immediate-early-CMV and gG pseudorabies virus promoters in transfected mammalian cells
Fri Sep 01 00:00:00 UTC 2006
Morphologic, phenotypic and functional characteristics of endothelial cells derived from human hepatic cavernous hemangioma.
Journal of vascular research
Zhang WJ,Ye LY,Wu LQ,Xin YL,Gu F,Niu JX,Yang ZH,Zhu GJ,Grau GE,Lou JN
MA5-11866 was used in western blot to study the morphological, phenotypic and functional characteristics of endothelial cells derived from human hepatic cavernous hemangioma
Thu Jan 04 00:00:00 UTC 2007
Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends.
The Journal of biological chemistry
Drouet J,Frit P,Delteil C,de Villartay JP,Salles B,Calsou P
MA5-11866 was used in immunoprecipitation to study the interaction of Artemis with proteins involved of the non-homologous end joining pathway
Fri Sep 22 00:00:00 UTC 2006
N-glycosylation affects the molecular organization and stability of E-cadherin junctions.
The Journal of biological chemistry
Liwosz A,Lei T,Kukuruzinska MA
MA5-11866 was used in immunocytochemistry to study the role of N-glycosylation in the molecular organization and stability of E-cadherin junctions
Fri Aug 11 00:00:00 UTC 2006
Human keratinocytes acquire cellular cytotoxicity under UV-B irradiation. Implication of granzyme B and perforin.
The Journal of biological chemistry
Hernandez-Pigeon H,Jean C,Charruyer A,Haure MJ,Titeux M,Tonasso L,Quillet-Mary A,Baudouin C,Charveron M,Laurent G
MA5-11866 was used in western blot to study the role of granzyme B and perforin in the acquisition of cellular cytotoxicity by human keratinocytes under UV-B irradiation
Fri May 12 00:00:00 UTC 2006
Dissecting the biological functions of Drosophila histone deacetylases by RNA interference and transcriptional profiling.
The Journal of biological chemistry
Foglietti C,Filocamo G,Cundari E,De Rinaldis E,Lahm A,Cortese R,Steinkühler C
MA5-11866 was used in western blot to study the biological functions of Drosophila histone deacetylases
Fri Jun 30 00:00:00 UTC 2006
Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter.
Nucleic acids research
Markusic D,Oude-Elferink R,Das AT,Berkhout B,Seppen J
MA5-11866 was used in western blot to study the potential of autoregulatory lentiviral vectors for thereapeutic gene delivery
Mon Apr 04 00:00:00 UTC 2005
RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance.
Clinical cancer research : an official journal of the American Association for Cancer Research
Duxbury MS,Ito H,Benoit E,Waseem T,Ashley SW,Whang EE
MA5-11866 was used in western blot to study the role of integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance
Sun May 01 00:00:00 UTC 2005
Stable RNA interference-mediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo.
Cancer research
Howard BA,Furumai R,Campa MJ,Rabbani ZN,Vujaskovic Z,Wang XF,Patz EF
MA5-11866 was used in western blot to study the effect of RNA-mediated suppression of cyclophilin A on non-small-cell lung tumor growth in vivo
Sat Oct 01 00:00:00 UTC 2005
The effect of isoforms of the cell polarity protein, human ASIP, on the cell cycle and Fas/FasL-mediated apoptosis in human hepatoma cells.
Cellular and molecular life sciences : CMLS
Hu Y,Fang C,Xu Y
MA5-11866 was used in western blot to study the effect of isoforms of the cell polarity protein, human ASIP, on the cell cycle and Fas/FasL-mediated apoptosis in human hepatoma cells
Thu Sep 01 00:00:00 UTC 2005
Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: functional androgen receptor requirement.
Endocrine-related cancer
Bidaux G,Roudbaraki M,Merle C,Crépin A,Delcourt P,Slomianny C,Thebault S,Bonnal JL,Benahmed M,Cabon F,Mauroy B,Prevarskaya N
MA5-11866 was used in western blot to study TRPM8 expression in human prostate secretory epithelial cells
Wed Jun 01 00:00:00 UTC 2005
Phosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.
Molecular and cellular biology
Rao VA,Fan AM,Meng L,Doe CF,North PS,Hickson ID,Pommier Y
MA5-11866 was used in western blot to study the role of the Bloom's syndrome protein in the signaling response to Top1-mediated replication DNA damage
Sat Oct 01 00:00:00 UTC 2005
Protein kinase C zeta associates with death inducing signaling complex and regulates Fas ligand-induced apoptosis.
Cellular signalling
Leroy I,de Thonel A,Laurent G,Quillet-Mary A
MA5-11866 was used in western blot to study whether PKC-zeta targets apical events of Fas signaling using Jurkat cells as a FasL-sensitive human T-cell model
Thu Sep 01 00:00:00 UTC 2005
Histone H4 post-translational modifications in chordate mitotic and endoreduplicative cell cycles.
Journal of cellular biochemistry
Spada F,Chioda M,Thompson EM
MA5-11866 was used in western blot to investigate histone H4 post-translational modifications during mitotic and endocycles of Oikopleura dioica in comparison with those in mitotic cycle of proliferating mammalian cells
Mon Aug 01 00:00:00 UTC 2005
Melatonin reduces prostate cancer cell growth leading to neuroendocrine differentiation via a receptor and PKA independent mechanism.
The Prostate
Sainz RM,Mayo JC,Tan DX,León J,Manchester L,Reiter RJ
MA5-11866 was used in western blot to study the mechanisms by which melatonin inhibits prostate cancer cell growth and induces neuroendocrine differentiation
Fri Apr 01 00:00:00 UTC 2005
Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication.
Virology
Domitrovich AM,Diebel KW,Ali N,Sarker S,Siddiqui A
MA5-11866 was used in western blot to study the role of La autoantigen and polypyrimidine tract-binding protein in HCV replication
Mon Apr 25 00:00:00 UTC 2005
Atypical endometrial stromal cells related with a polypoid leiomyoma with bizarre nuclei: a case report.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
Usubütün A,Karaman N,Ayhan A,Küçükali T
MA5-11866 was used in immunohistochemistry to report on a case of atypical endometrial stromal cells related to a polypoid leiomyoma with bizarre nuclei
Sat Oct 01 00:00:00 UTC 2005
Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor.
Biochemical and biophysical research communications
Hamdi HK,Castellon R
MA5-11866 was used in immunocytochemistry to study the anti-tumor and cytoskeletal disruptive activity of the non-toxic olive iridoid Oleuropein
Fri Sep 02 00:00:00 UTC 2005
Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells.
The Journal of biological chemistry
Thebault S,Lemonnier L,Bidaux G,Flourakis M,Bavencoffe A,Gordienko D,Roudbaraki M,Delcourt P,Panchin Y,Shuba Y,Skryma R,Prevarskaya N
MA5-11866 was used in western blot to study the role of the cold/menthol-sensitive TRPM8 channel in Ca(2+) metabolism in human prostate cancer epithelial cells
Fri Nov 25 00:00:00 UTC 2005
Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells.
Molecular cell
Izsvák Z,Stüwe EE,Fiedler D,Katzer A,Jeggo PA,Ivics Z
MA5-11866 was used in immunoprecipitation and western blot to study the role of DNA repair factors in Sleeping Beauty transposition in mammalian cells
Fri Jan 30 00:00:00 UTC 2004
The Kaposi's sarcoma-associated herpesvirus K-bZIP protein represses transforming growth factor beta signaling through interaction with CREB-binding protein.
Oncogene
Tomita M,Choe J,Tsukazaki T,Mori N
MA5-11866 was used in western blot to study the mechanism by which Kaposi's sarcoma-associated herpesvirus K-bZIP protein represses TGF-beta signaling
Thu Oct 28 00:00:00 UTC 2004
Involvement of extracellular signal-regulated kinase/mitogen-activated protein kinase pathway in multidrug resistance induced by HBx in hepatoma cell line.
World journal of gastroenterology
Guan J,Chen XP,Zhu H,Luo SF,Cao B,Ding L
MA5-11866 was used in western blot to investigate the role of HBx protein on the occurrence of multidrug resistance in hepatoma cell line
Wed Dec 01 00:00:00 UTC 2004
Ligation of EphA2 by Ephrin A1-Fc inhibits pancreatic adenocarcinoma cellular invasiveness.
Biochemical and biophysical research communications
Duxbury MS,Ito H,Zinner MJ,Ashley SW,Whang EE
MA5-11866 was used in western blot to study the effect of EphA2 overexpression and ligation by chimeric Ephrin A1-Fc on the invasive phenotype of pancreatic adenocarcinoma cells
Fri Aug 06 00:00:00 UTC 2004
Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing.
Nucleic acids research
Onclercq-Delic R,Calsou P,Delteil C,Salles B,Papadopoulo D,Amor-Guéret M
MA5-11866 was used in immunoprecipitation to study the potential anti-recombinogenic role of BLM DNA helicase in double-strand break processing
Sat Nov 01 00:00:00 UTC 2003
The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition.
Nucleic acids research
Zayed H,Izsvák Z,Khare D,Heinemann U,Ivics Z
MA5-11866 was used in immunoprecipitation to study the role of the DNA-bending protein HMGB1 in Sleeping Beauty transposition
Thu May 01 00:00:00 UTC 2003
Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.
Journal of molecular biology
Calsou P,Delteil C,Frit P,Drouet J,Salles B
MA5-11866 was used in immunoprecipitation to investigate the relationship and assembly of specific proteins during DNA repair process
Fri Feb 07 00:00:00 UTC 2003
Measles virus-induced modulation of host-cell gene expression.
The Journal of general virology
Bolt G,Berg K,Blixenkrone-Møller M
MA5-11866 was used in western blot to study measles virus-induced modulation of host-cell gene expression by human peripheral blood mononuclear cells
Wed May 01 00:00:00 UTC 2002
