Product References
Interaction of delta-like 1 homolog (Drosophila) with prohibitins and its impact on tumor cell clonogenicity.
Molecular cancer research : MCR
Begum A,Lin Q,Yu C,Kim Y,Yun Z
MA5-12855 was used in immunoprecipitation and western blot to study the role in maintaining cancer cell clonogenicity of the interaction of DLK1 with prohibitin-1 and prohibitin-2
Wed Jan 01 00:00:00 UTC 2014
Prohibitin is involved in the activated internalization and degradation of protease-activated receptor 1.
Biochimica et biophysica acta
Wang YJ,Guo XL,Li SA,Zhao YQ,Liu ZC,Lee WH,Xiang Y,Zhang Y
MA5-12855 was used in flow cytometry to study the mechanism by which prohibitin modulates PAR1 internalization and degradation
Tue Jul 01 00:00:00 UTC 2014
GRSF1 regulates RNA processing in mitochondrial RNA granules.
Cell metabolism
Jourdain AA,Koppen M,Wydro M,Rodley CD,Lightowlers RN,Chrzanowska-Lightowlers ZM,Martinou JC
MA5-12855 was used in western blot to study the localization of a GRSF1 isoform to the mitochondrial matrix and its role in RNA processing
Tue Mar 05 00:00:00 UTC 2013
Proteomic, cellular, and network analyses reveal new DUSP3 interactions with nucleolar proteins in HeLa cells.
Journal of proteome research
Panico K,Forti FL
MA5-12855 was used in western blot to identify novel interactions of DISP3 with nucleolar proteins in HeLa cells exposed to UV/gamma irradiation
Fri Dec 06 00:00:00 UTC 2013
Prohibitins function as endogenous ligands for Siglec-9 and negatively regulate TCR signaling upon ligation.
Biochemical and biophysical research communications
Yurugi H,Tanida S,Akita K,Ishida A,Toda M,Nakada H
MA5-12855 was used in western blot to study the role of prohibitins as endogenous Siglec-9 ligands that inhibit ERK signaling and IL-12 production by Jurkat cells
Fri May 03 00:00:00 UTC 2013
Differential expression and subcellular localization of Prohibitin 1 are related to tumorigenesis and progression of non-small cell lung cancer.
International journal of clinical and experimental pathology
Jiang P,Xiang Y,Wang YJ,Li SM,Wang Y,Hua HR,Yu GY,Zhang Y,Lee WH,Zhang Y
MA5-12855 was used in flow cytometry, immunohistochemistry, and western blot to study the clinical significance of Prohibitin-1 expression in non-small cell lung cancer
Mon Jun 09 00:00:00 UTC 2014
Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression.
Arthritis and rheumatism
Picard C,Pellicelli M,Taheri M,Lavoie JF,Doucet R,Wang D,Bernard L,Bouhanik S,Lavigne P,Moreau A
MA5-12855 was used in immunocytochemistry to study PITX1 down-regulation in osteoarthritic chondrocytes and the mechanistic role of nuclear prohibitin-1
Mon Apr 01 00:00:00 UTC 2013
Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells.
EMBO molecular medicine
Leanza L,Henry B,Sassi N,Zoratti M,Chandy KG,Gulbins E,Szabò I
MA5-12855 was used in western blot to study the ability of inhibitors of mitochondrial Kv1.3 channels to induce Bax/Bak-independent death of cancer cells
Sun Jul 01 00:00:00 UTC 2012
Androgen-regulated processing of the oncomir miR-27a, which targets Prohibitin in prostate cancer.
Human molecular genetics
Fletcher CE,Dart DA,Sita-Lumsden A,Cheng H,Rennie PS,Bevan CL
MA5-12855 was used in western blot to study the mechanism of androgen-modulated miR-27a processing in prostate cancer
Sun Jul 15 00:00:00 UTC 2012
Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.
Current medicinal chemistry
Leanza L,Zoratti M,Gulbins E,Szabò I
MA5-12855 was used in western blot to study the role of the Kv 1.3 and Kv 1.5 potassium channels in the induction of macrophage apoptosis
Wed May 22 00:00:00 UTC 2013
Expression of prohibitins on the surface of activated T cells.
Biochemical and biophysical research communications
Yurugi H,Tanida S,Ishida A,Akita K,Toda M,Inoue M,Nakada H
MA5-12855 was used in western blot to study the expression and role of prohibitins on the surface of activated T cells
Fri Apr 06 00:00:00 UTC 2012
Induction of the permeability transition pore in cells depleted of mitochondrial DNA.
Biochimica et biophysica acta
Masgras I,Rasola A,Bernardi P
MA5-12855 was used in western blot to study the function of the permeability transition pore in cells lacking mitochondrial DNA
Mon Oct 01 00:00:00 UTC 2012
Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry.
Molecular systems biology
Orr SJ,Boutz DR,Wang R,Chronis C,Lea NC,Thayaparan T,Hamilton E,Milewicz H,Blanc E,Mufti GJ,Marcotte EM,Thomas NS
MA5-12855 was used in western blot to study the proteomic changes and protein interaction networks involved in the entry of human T-cells into the cell cycle
Tue Mar 13 00:00:00 UTC 2012
Manganese superoxide dismutase: a regulator of T cell activation-induced oxidative signaling and cell death.
Biochimica et biophysica acta
Kamiński MM,Röth D,Sass S,Sauer SW,Krammer PH,Gülow K
MA5-12855 was used in western blot to study the regulatory role of manganese superoxide dismutase in T-cell activation
Tue May 01 00:00:00 UTC 2012
General Sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMAC.
PloS one
Quast SA,Berger A,Buttstädt N,Friebel K,Schönherr R,Eberle J
MA5-12855 was used in western blot to study the mechanism by which the selective KCa3.1 inhibitor TRAM-34 sensitizes melanoma cells to apoptosis induced by TRAIL
Wed Dec 12 00:00:00 UTC 2012
All-trans retinoic acid treatment is associated with prohibitin expression in renal interstitial fibrosis rats.
International journal of molecular sciences
Zhou TB,Qin YH,Li ZY,Xu HL,Zhao YJ,Lei FY
MA5-12855 was used in immunohistochemistry to study the association between treatment with all-trans retinoic acid and prohibitin expression in rats suffering renal interstitial fibrosis
Mon Jul 06 00:00:00 UTC 2015
Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis.
Inflammatory bowel diseases
Theiss AL,Laroui H,Obertone TS,Chowdhury I,Thompson WE,Merlin D,Sitaraman SV
MA5-12855 was used in western blot to study the therapeutic of potential adenovirus- and nanoparticle-mediated delivery for restoring epithelial prohibitin levels in experimental colitis in mice
Sun May 01 00:00:00 UTC 2011
The dynamic equilibrium between ATP synthesis and ATP consumption is lower in isolated mitochondria from myotubes established from type 2 diabetic subjects compared to lean control.
Biochemical and biophysical research communications
Minet AD,Gaster M
MA5-12855 was used in western blot to study ATP synthesis and consumption in skeletal muscle mitochondria isolated from type 2 diabetics and lean individuals
Fri Jun 17 00:00:00 UTC 2011
EndoG links Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes.
PloS one
Zhang J,Ye J,Altafaj A,Cardona M,Bahi N,Llovera M,Cañas X,Cook SA,Comella JX,Sanchis D
MA5-12855 was used in western blot to study the role of EndoG in Bnip3-induced mitochondrial damage and caspase-independent DNA fragmentation in ischemic cardiomyocytes
Thu Mar 17 00:00:00 UTC 2011
Proteomic study of thyroid tumors reveals frequent up-regulation of the Ca2+ -binding protein S100A6 in papillary thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association
Sofiadis A,Dinets A,Orre LM,Branca RM,Juhlin CC,Foukakis T,Wallin G,Höög A,Hulchiy M,Zedenius J,Larsson C,Lehtiö J
MA5-12855 was used in western blot to investigate the changes of S100A6 level in papillary thyroid carcinoma
Fri Oct 01 00:00:00 UTC 2010
An unusual function of RON receptor tyrosine kinase as a transcriptional regulator in cooperation with EGFR in human cancer cells.
Carcinogenesis
Liu HS,Hsu PY,Lai MD,Chang HY,Ho CL,Cheng HL,Chen HT,Lin YJ,Wu TJ,Tzai TS,Chow NH
MA5-12855 was used in western blot to investigate the role of RON for gene expression in human cancer cells
Sun Aug 01 00:00:00 UTC 2010
Proteome analysis of ultraviolet-B-induced protein expression in vitro human dermal fibroblasts.
Photodermatology, photoimmunology & photomedicine
Yan Y,Xu H,Peng S,Zhao W,Wang B
MA5-12855 was used in western blot to study the effect of UVB irradiation on the proteome of human dermal fibroblasts
Wed Dec 01 00:00:00 UTC 2010
An investigation of the occurrence and properties of the mitochondrial intermediate-conductance Ca2+-activated K+ channel mtKCa3.1.
Biochimica et biophysica acta
Sassi N,De Marchi U,Fioretti B,Biasutto L,Gulbins E,Franciolini F,Szabò I,Zoratti M
MA5-12855 was used in western blot to characterize the mitochondrial intermediate-conductance calcium-activated potassium channel mtKCa3.1
Mon Jan 10 00:00:00 UTC 2011
Overexpression of follicle-stimulating hormone receptor facilitates the development of ovarian epithelial cancer.
Cancer letters
Zhang Z,Jia L,Feng Y,Zheng W
MA5-12855 was used in western blot to study the role of FSH receptor overexpression in the development of ovarian epithelial cancer
Mon Jun 08 00:00:00 UTC 2009
Contribution of nitric oxide, superoxide anion, and peroxynitrite to activation of mitochondrial apoptotic signaling in hippocampal CA3 subfield following experimental temporal lobe status epilepticus.
Epilepsia
Chuang YC,Chen SD,Liou CW,Lin TK,Chang WN,Chan SH,Chang AY
MA5-12855 was used in western blot to study the role of NO, superoxide anion, and peroxynitrite in apoptotic cell death in the hippocampal CA3 subfield in temporal lobe status epilepticus
Wed Apr 01 00:00:00 UTC 2009
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair.
Human molecular genetics
Rothfuss O,Fischer H,Hasegawa T,Maisel M,Leitner P,Miesel F,Sharma M,Bornemann A,Berg D,Gasser T,Patenge N
MA5-12855 was used in western blot to investigate the role of parkin in mitochondrial DNA repair
Thu Oct 15 00:00:00 UTC 2009
Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells.
Cell calcium
De Marchi U,Sassi N,Fioretti B,Catacuzzeno L,Cereghetti GM,Szabò I,Zoratti M
MA5-12855 was used in western blot to investigate the intermediate conductance calcium-activated potassium channel(Kca 3.1) in the inner membrane of colon cancer cell mitochondria
Fri May 01 00:00:00 UTC 2009
Spontaneous internalization of IVIg in activated B cells.
Immunology letters
Proulx DP,Aubin E,Lemieux R,Bazin R
MA5-12855 was used in western blot to study the mechanism for the effect of IVIg in B cells
Thu May 14 00:00:00 UTC 2009
Cellular vimentin content regulates the protein level of hepatitis C virus core protein and the hepatitis C virus production in cultured cells.
Virology
Nitahara-Kasahara Y,Fukasawa M,Shinkai-Ouchi F,Sato S,Suzuki T,Murakami K,Wakita T,Hanada K,Miyamura T,Nishijima M
MA5-12855 was used in western blot to investigate the effect of hepatic vimentin on hepatitis C virus and viral core protein expression
Tue Jan 20 00:00:00 UTC 2009
Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.
Molecular and cellular biology
Schmidt VA,Chiariello CS,Capilla E,Miller F,Bahou WF
MA5-12855 was used in western blot to investigate the distinct roles of multidomain scaffolding protein IQGAP1 and 2 in hepatocellular carcinogenesis
Sat Mar 01 00:00:00 UTC 2008
Structural analysis of tissues affected by cytochrome C oxidase deficiency due to mutations in the SCO2 gene.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Vesela K,Hulkova H,Hansikova H,Zeman J,Elleder M
MA5-12855 was used in immunohistochemistry to investigate the clinicopathological features of cytochrome C oxidase deficiency due to SCO2 mutations
Tue Jan 01 00:00:00 UTC 2008
Purification and proteomic analysis of the mouse liver mitochondrial inner membrane.
Methods in molecular biology (Clifton, N.J.)
Da Cruz S,Martinou JC
MA5-12855 was used in western blot to develop a novel method to determine the mitochondrial inner membrane proteome
Mon Aug 11 00:00:00 UTC 2008
Neurolysosomal pathology in human prosaposin deficiency suggests essential neurotrophic function of prosaposin.
Acta neuropathologica
Sikora J,Harzer K,Elleder M
MA5-12855 was used in immunohistochemistry to study the role of prosaposin
Thu Feb 01 00:00:00 UTC 2007
Development of the terminally differentiated state sensitizes epiphyseal chondrocytes to apoptosis through caspase-3 activation.
Journal of cellular physiology
Pucci B,Adams CS,Fertala J,Snyder BC,Mansfield KD,Tafani M,Freeman T,Shapiro IM
MA5-12855 was used in western blot to study the role of mitochondria in the sensitization to aopoptosis of terminally differentiated epiphyseal chondrocytes
Thu Mar 01 00:00:00 UTC 2007
Upregulation of nitric oxide synthase II contributes to apoptotic cell death in the hippocampal CA3 subfield via a cytochrome c/caspase-3 signaling cascade following induction of experimental temporal lobe status epilepticus in the rat.
Neuropharmacology
Chuang YC,Chen SD,Lin TK,Liou CW,Chang WN,Chan SH,Chang AY
MA5-12855 was used in western blot to study the role of NOS II in apoptotic cell death in the hippocampal CA3 subfield in temporal lobe status epilepticus
Sun Apr 01 00:00:00 UTC 2007
Prohibitin suppresses renal interstitial fibroblasts proliferation and phenotypic change induced by transforming growth factor-beta1.
Molecular and cellular biochemistry
Guo W,Xu H,Chen J,Yang Y,Jin JW,Fu R,Liu HM,Zha XL,Zhang ZG,Huang WY
MA5-12855 was used in immunocytochemistry, immunohistochemistry, and western blot to study the role of prohibitin in suppressing renal interstitial fibroblast proliferation and phenotypic changes induced by TGF-beta1
Mon Jan 01 00:00:00 UTC 2007
Differential regulation of human YY1 and caspase 7 promoters by prohibitin through E2F1 and p53 binding sites.
The Biochemical journal
Joshi B,Rastogi S,Morris M,Carastro LM,DeCook C,Seto E,Chellappan SP
MA5-12855 was used in ChIP assay to investigate the regulatory effect of prohibitin on human YY1 and caspase 7 promoters
Mon Jan 01 00:00:00 UTC 2007
Prohibitin in the pathogenesis of transitional cell bladder cancer.
Anticancer research
Wu TF,Wu H,Wang YW,Chang TY,Chan SH,Lin YP,Liu HS,Chow NH
MA5-12855 was used in western blot to study prohibitin and its role in transitional cell bladder cancer pathogenesis
Thu May 10 00:00:00 UTC 2007
A case of excessive autophagocytosis with multiorgan involvement and low clinical penetrance.
Ceskoslovenska patologie
Sikora J,Dvoráková L,Vlásková H,Stolnaja L,Betlach J,Spacek J,Elleder M
MA5-12855 was used in immunohistochemistry to study a case of a female patient with excessive autophagocytosis
Sun Jul 01 00:00:00 UTC 2007
Heat shock protein 60 or 70 activates nitric-oxide synthase (NOS) I- and inhibits NOS II-associated signaling and depresses the mitochondrial apoptotic cascade during brain stem death.
The Journal of biological chemistry
Chan JYH,Cheng HL,Chou JLJ,Li FCH,Dai KY,Chan SHH,Chang AYW
MA5-12855 was used in western blot to study the neuroprotective roles of HSP60 and HSP70 in the rostral ventrolateral medulla during brain stem death
Fri Feb 16 00:00:00 UTC 2007
Heat shock protein 60 in rostral ventrolateral medulla reduces cardiovascular fatality during endotoxaemia in the rat.
The Journal of physiology
Chang AY,Chan JY,Chou JL,Li FC,Dai KY,Chan SH
MA5-12855 was used in western blot to study the mechanism by which HSP60 reduces cardiovascular fatality during brain stem death
Sat Jul 15 00:00:00 UTC 2006
Differential regulation of metabolic genes in skeletal muscle during starvation and refeeding in humans.
The Journal of physiology
Tsintzas K,Jewell K,Kamran M,Laithwaite D,Boonsong T,Littlewood J,Macdonald I,Bennett A
MA5-12855 was used in western blot to study the regulation of human sketetal muscle metabolic genes during starvation and refeeding
Tue Aug 15 00:00:00 UTC 2006
Molecular determinants for subcellular localization of hepatitis C virus core protein.
Journal of virology
Suzuki R,Sakamoto S,Tsutsumi T,Rikimaru A,Tanaka K,Shimoike T,Moriishi K,Iwasaki T,Mizumoto K,Matsuura Y,Miyamura T,Suzuki T
MA5-12855 was used in western blot to study the mechanisms controlling the subcellular localization of hepatitis C virus core protein
Sat Jan 01 00:00:00 UTC 2005
Proteomic analysis of redox- and ErbB2-dependent changes in mammary luminal epithelial cells using cysteine- and lysine-labelling two-dimensional difference gel electrophoresis.
Proteomics
Chan HL,Gharbi S,Gaffney PR,Cramer R,Waterfield MD,Timms JF
MA5-12855 was used in western blot to study redox- and ErbB2-dependent changes in mammary luminal epithelial cells
Fri Jul 01 00:00:00 UTC 2005
Protein expression profiles in adenocarcinomas and squamous cell carcinomas of the lung generated using tissue microarrays.
The Journal of pathology
Ullmann R,Morbini P,Halbwedl I,Bongiovanni M,Gogg-Kammerer M,Papotti M,Gabor S,Renner H,Popper HH
MA5-12855 was used in immunohistochemistry to establish the protein expression profiles for lung neoplasms
Thu Jul 01 00:00:00 UTC 2004
A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway.
The Journal of biological chemistry
Li Q,Ching AK,Chan BC,Chow SK,Lim PL,Ho TC,Ip WK,Wong CK,Lam CW,Lee KK,Chan JY,Chui YL
MA5-12855 was used in western blot to investigate the role of brain and reproductive organ-expressed protein BRE in death receptor-mediated apoptosis
Fri Dec 10 00:00:00 UTC 2004
