Invitrogen

RPE65 Monoclonal Antibody (401.8B11.3D9), DyLight™ 650

产品信息

MA5-16041

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:5,000-1:10,000

免疫组化（石蜡） (IHC (P))

1:250

免疫组化（冰冻） (IHC (F))

1:250

免疫细胞化学 (ICC/IF)

1:10-1:500

流式细胞分析 (Flow)

Assay-Dependent

产品规格

种属反应

Bovine, Dog, Chicken, Human, Mouse, Non-human primate, Pig, Rat, Xenopus

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

401.8B11.3D9

抗原

Bovine RPE microsomal membrane proteins.

查看免疫原

偶联物

DyLight™ 650 DyLight™ 650 DyLight™ 650

激发/发射光谱

651/673 nm 查看光谱

形式

Liquid

浓度

0.68 mg/mL

纯化类型

Protein G

保存液

50mM sodium borate

内含物

0.05% sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

AB_11152019

靶标信息

RPE65 is a major protein of the retinal pigment epithelium (RPE). RPE65 is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: All-trans-retinyl-palmitate hydrolase; BCO family, member 3; Lutein isomerase; Meso-zeaxanthin isomerase; modifier of retinal degeneration 1; p63; RBP-binding membrane protein; retinal pigment epithelium 65-like; retinal pigment epithelium abundant protein RPE65; retinal pigment epithelium specific protein 65; retinal pigment epithelium, 65 kDa; Retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific 65kD protein; retinal pigment epithelium-specific protein (65kD); retinal pigment epithelium-specific protein 65kDa; Retinitis pigmentos; retinitis pigmentosa 20 (autosomal recessive); Retinoid isomerohydrolase; Retinol isomerase; RPE65; rpe65 gene for retinal pigment epithelium-specific protein; RPE65, retinoid isomerohydrolase; truncated RPE65

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基因别名: 65kDa; A930029L06Rik; BCO3; LCA2; Mord1; mRPE65; rd12; RP20; RPE65; sRPE65