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This antibody recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
The protein encoded by the PCLO gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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蛋白别名: Aczonin; PCLO; Protein piccolo
基因别名: ACZ; KIAA0559; PCH3; PCLO
UniProt ID: (Human) Q9Y6V0
Entrez Gene ID: (Human) 27445