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LIMP2 Antibody (MA5-41013) in Flow
Flow cytometric analysis of Mouse LIMP2 expression in spleen lymphocytes. The cells were treated according to manufacturer’s manual, and then stained with LIMP2 Recombinant Rabbit Monoclonal Antibody (052), PE (Product # MA5-41013). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
产品信息
MA5-41013
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
052
抗原
Recombinant Mouse LIMP-2/SCARB2/CD36L2 protein
偶联物
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein A
保存液
PBS with 0.5% BSA
内含物
0.09% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2898774
产品详细信息
May be stored for twelve months without detectable loss of activity. Protect from prolonged exposure to light and do not freeze. Sodium azide is toxic to cells and should be disposed of properly so flush with large volumes of water during disposal.
靶标信息
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII differs from SR-BI in that the encoded c-terminal cytoplasmic domain is almost completely different. SR-BII binds HDLs and mediates selective uptake of HDL cholesteryl ester, but with an approximately 4-fold lower efficiency than SR-BI. Nuclease protection assays show SR-BII to be abundant in mouse tissues expressing SR-BI, with SR-BII expression found in liver, adrenal glands, and testes. Although the role of SR-BII is not completely clear, research suggests that it may be a functional HDL receptor. In addition, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with the SR-BII isoform mediating selective transfer of lipid between HDL and cells. The relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: 85 kDa lysosomal membrane sialoglycoprotein; CD 36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2; CD36 molecule; LGP85; LIMP II; Lysosome membrane protein 2; Lysosome membrane protein II; Scavenger receptor class B member 2; sCD 36; sCD36; soluble CD 36; soluble CD36; SR-B2
基因别名: 9330185J12Rik; Cd36l2; LGP85; LIMP-2; MLGP85; Scarb2
UniProt ID: (Mouse) O35114
Entrez Gene ID: (Mouse) 12492
