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MAD2 Antibody (MA5-35113) in IHC (P)
Immunohistochemistry analysis of MAD2 in paraffin-embedded mouse kidney. Samples were incubated with MAD2 Monoclonal antibody (Product # MA5-35113) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
MA5-35113
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC0603
抗原
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human MAD2/MAD2L1 (Q13257)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2849018
产品详细信息
Immunogen sequence: EQLKDWLYKC SVQKLVVVIS NIESGEVLER WQFDIECDKT AKDDSAPREK SQKAIQDEIR SVIRQITATV TFLPLLEVSC S
靶标信息
Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HsMAD2; MAD2 (mitotic arrest deficient, homolog)-like 1; MAD2 (mitotic arrest deficient, yeast, homolog)-like 1; MAD2-like 1; MAD2-like protein 1; MadL1; Mitotic arrest deficient 2-like protein 1; mitotic arrest deficient, yeast, homolog-like 1; Mitotic spindle assembly checkpoint protein MAD2A
基因别名: AA673185; HSMAD2; MAD2; Mad2a; MAD2L1
UniProt ID: (Human) Q13257, (Mouse) Q9Z1B5
Entrez Gene ID: (Human) 4085, (Rat) 297176, (Mouse) 56150
mitotic sister chromatid segregation
mitotic cell cycle checkpoint
mitotic spindle assembly checkpoint
negative regulation of protein catabolic process
negative regulation of apoptotic process
negative regulation of mitotic cell cycle
positive regulation of mitotic cell cycle spindle assembly checkpoint
negative regulation of ubiquitin protein ligase activity
cell cycle
mitotic nuclear division
negative regulation of mitotic metaphase/anaphase transition
cell division
sister chromatid cohesion
anaphase-promoting complex-dependent catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
