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MAGE1 Antibody (35-6300) in IHC
Veterinary sciences 2020 -
Figure 3 Positive cross-reactivity of MAb 6C1, mammary gland tumors and canines. Location of MAGE expression in the complex carcinoma type of malignant mammary gland tumor section Ma1: ( a ) HE stained, 40x; ( b ) IHC-stained-positive, 40x; ( c ) IHC-stained-positive, 100x black arrows are representative of nuclear expression pattern; red arrows are representative of nuclear-cytoplasmic expression pattern.
产品信息
35-6300
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Dog,
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
6C1
抗原
Full-length recombinant human MAGE-A.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.1% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2533216
靶标信息
Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). An important group of antigens is coded by the MAGE family of genes. It was identified that melanoma associated with antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various hisological tyoes (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Antigen MZ2-E; Cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CT1.1; mage 1; mage-1; MAGE-1 antigen; melanoma antigen family A 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); melanoma antigen family A1; melanoma antigen MAGE-1; Melanoma-associated antigen 1; melanoma-associated antigen MZ2-E
基因别名: CT1.1; MAGE1; MAGE1A; MAGEA1
UniProt ID: (Human) P43355
Entrez Gene ID: (Human) 4100
