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MAGEA3 Chimeric Antibody (MA5-51710) in ICC/IF
Immunocytochemistry analysis of MAGEA3 in paraformaldehyde fixed HeLa cells using MAGEA3 Chimeric Recombinant Rabbit Monoclocal Antibody (Product # MA5-51710) at a 1:1,000 dilution for 1h followed by Alexa Fluor 488 secondary antibody (1:1,500 dilution), showing nuclear staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom: primary antibody, DAPI, merged channels and an isotype... View More
产品信息
MA5-51710
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
21B4
抗原
The original antibody was isolated from a patient suffering from a tumor expressing a tumor specific antigen like MAGE-A3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.02% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
This antibody binds human MAGEA3 and MAGEA6, but does not cross react with other members of the MAGE family like MAGE-A1, MAGE-A4 and MAGE-A10. MAGE-A3 is a tumor specific antigen and it is expressed on many tumors like melanoma, non-small cell lung cancer, hematologic malignancies, and others.
靶标信息
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Antigen MZ2-D; Cancer/testis antigen 1.3; cancer/testis antigen family 1, member 3; CT1.3; MAGE-3 antigen; melanoma antigen family A, 3; melanoma antigen family A3; Melanoma-associated antigen 3; MGC14613
基因别名: CT1.3; HIP8; HYPD; MAGE3; MAGEA3; MAGEA6
UniProt ID: (Human) P43357
Entrez Gene ID: (Human) 4102
