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Immunogen sequence: AQAPTTEEQE AAVSSSSPLV PGTLEEVPAA ESAGPPQSPQ GASALPTTIS FTCWRQPNEG SSSQEEEGPS TSPDAESLFR EALSNKVDEL AHFLLRKYRA KELVTKAEML ERVIKNYKRC FPVIFGKASE SLKMIFGIDV KEVDPASNTY TLVTCLGLSY DGLLGNNQIF PKTGLLIIVL GTIAMEGDSA SEEEIWEELG VMGVYDGREH TVYGEPRKLL TQDWVQENYL EYRQVPGSNP ARYEFLWGPR ALAETSYVKV LEHVVRVNAR VRIAYPSLRE AALLEEEEGV; Positive Samples: A-375, Mouse liver, Rat liver
MAGEA4 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cancer/testis antigen 1.4; cancer/testis antigen family 1, member 4; CT1.4; MAGE-4 antigen; MAGE-41 antigen; MAGE-X2 antigen; melanoma antigen family A, 4; melanoma antigen family A4; melanoma antigen, family A, 4; Melanoma-associated antigen 4; MGC21336
基因别名: CT1.4; MAGE-41; Mage-a4; MAGE-X2; MAGE4; MAGE4A; MAGE4B; MAGEA4
UniProt ID: (Human) P43358
Entrez Gene ID: (Human) 4103, (Rat) 689858, (Mouse) 17140