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MAGED1 Antibody (PA5-88059) in IHC (P)
Immunohistochemistry analysis of MAGED1 in paraffin-embedded human colon carcinoma. Samples were incubated with MAGED1 Polyclonal antibody (Product # PA5-88059) using a dilution of 1:500 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
产品信息
PA5-88059
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 635-834 of human MAGED1/NRAGE (NP_0010053331)
偶联物
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804621
产品详细信息
Immunogen sequence: EAVLWEALRK MGLRPGVRHP LLGDLRKLLT YEFVKQKYLD YRRVPNSNPP EYEFLWGLRS YHETSKMKVL RFIAEVQKRD PRDWTAQFME AADEALDALD AAAAEAEARA EARTRMGIGD EAVSGPWSWD DIEFELLTWD EEGDFGDPWS RIPFTFWARY HQNARSRFPQ TFAGPIIGPG GTASANFAAN FGAIGFFWVE; Positive Samples: Mouse liver, Mouse lung, Rat lung, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein
靶标信息
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 11B6; BCG-1; Dlxin-1; JCL-1; MAGE tumor antigen CCF; MAGE-D1 antigen; Maged2; melanoma antigen family D, 1; melanoma antigen family D1; Melanoma-associated antigen D1; Neurotrophin receptor-interacting MAGE homolog; Sertoli cell necdin-related gene protein 1; SNERG-1
基因别名: 2810433C11Rik; 5430405L04Rik; Dlixin; DLXIN-1; Dlxin1; DXBwg1492e; MAGE-D1; MAGED1; mFLJ00163; NRAGE; PP2250; PRO2292
UniProt ID: (Human) Q9Y5V3, (Mouse) Q9QYH6, (Rat) Q9ES73
Entrez Gene ID: (Human) 9500, (Mouse) 94275, (Rat) 84469
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
circadian regulation of gene expression
regulation of circadian rhythm
regulation of apoptotic process
positive regulation of MAP kinase activity
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
negative regulation of epithelial cell proliferation
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of apoptotic signaling pathway
rhythmic process
JUN phosphorylation
