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产品信息
PA5-21601
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1393 and 1455 of MAGI2 (Uniprot ID#Q86UL8)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11157438
产品详细信息
Recommended positive controls: A431, H1299, HeLa, HepG2, Raji.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. The MGC Project Team, Genome Res. 14:2121-2127(2004). Devroe E., J. Biol. Chem. 279:24444-24451(2004).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activin receptor interacting protein 1; AIP-1; Atrophin-1-interacting protein 1; Atrophin-1-interacting protein A; MAGI-2; Membrane-associated guanylate kinase inverted 2; Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2
基因别名: ACVRINP1; ACVRIP1; AIP-1; AIP1; ARIP1; KIAA0705; MAGI-2; MAGI2; SSCAM
UniProt ID: (Human) Q86UL8
Entrez Gene ID: (Human) 9863
positive regulation of receptor internalization
planar cell polarity pathway involved in axis elongation
negative regulation of cell proliferation
positive regulation of neuron projection development
negative regulation of cell migration
positive regulation of phosphoprotein phosphatase activity
negative regulation of activin receptor signaling pathway
nerve growth factor signaling pathway
receptor clustering
protein heterooligomerization
negative regulation of protein kinase B signaling
SMAD protein signal transduction
mitotic cell cycle arrest
glomerular visceral epithelial cell development
neuroligin clustering involved in postsynaptic membrane assembly
cellular response to nerve growth factor stimulus
positive regulation of synaptic vesicle clustering
