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Product Details
H00010892-D01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MALT1 (NP_776216.1, 1 a.a. approximately 813 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSLLGDPLQA LPPSAAPTGP LLAPPAGATL NRLREPLLRR LSELLDQAPE GRGWRRLAEL AGSRGRLRLS CLDLEQCSLK VLEPEGSPSL CLLKLMGEKG CTVTELSDFL QAMEHTEVLQ LLSPPGIKIT VNPESKAVLA GQFVKLCCRA TGHPFVQYQW FKMNKEIPNG NTSELIFNAV HVKDAGFYVC RVNNNFTFEF SQWSQLDVCD IPESFQRSVD GVSESKLQIC VEPTSQKLMP GSTLVLQCVA VGSPIPHYQW FKNELPLTHE TKKLYMVPYV DLEHQGTYWC HVYNDRDSQD SKKVEIIIDE LNNLGHPDNK EQTTDQPLAK DKVALLIGNM NYREHPKLKA PLVDVYELTN LLRQLDFKVV SLLDLTEYEM RNAVDEFLLL LDKGVYGLLY YAGHGYENFG NSFMVPVDAP NPYRSENCLC VQNILKLMQE KETGLNVFLL DMCRKRNDYD DTIPILDALK VTANIVFGYA TCQGAEAFEI QHSGLANGIF MKFLKDRLLE DKKITVLLDE VAEDMGKCHL TKGKQALEIR SSLSEKRALT DPIQGTEYSA ESLVRNLQWA KAHELPESMC LKFDCGVQIQ LGFAAEFSNV MIIYTSIVYK PPEIIMCDAY VTDFPLDLDI DPKDANKGTP EETGSYLVSK DLPKHCLYTR LSSLQKLKEH LVFTVCLSYQ YSGLEDTVED KQEVNVGKPL IAKLDMHRGL GRKTCFQTCL MSNGPYQSSA ATSGGAGHYH SLQDPFHGVY HSHPGNPSNV TPADSCHCSR TPDAFISSFA HHASCHFSRS NVPVETTDEI PFSFSDRLRI SEK
Target Information
MALT1/Paracaspase (MALT1) was independently identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000). MALT1 is a caspase-like protein that contains an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: caspase-like protein; DKFZp434L132; MALT lymphoma-associated translocation; malt-1; MALT1 protease; mucosa associated lymphoid tissue lymphoma translocation gene 1; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; Paracaspase; paracaspase 1; paracaspase-1
Gene Aliases: IMD12; MALT1; MLT; MLT1; PCASP1
UniProt ID: (Human) Q9UDY8
Entrez Gene ID: (Human) 10892
B-1 B cell differentiation
stimulatory C-type lectin receptor signaling pathway
response to molecule of bacterial origin
positive regulation of T cell cytokine production
proteolysis
defense response
activation of NF-kappaB-inducing kinase activity
response to fungus
protein ubiquitination
positive regulation of protein ubiquitination
positive regulation of interleukin-2 production
Fc-epsilon receptor signaling pathway
T cell proliferation
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
T cell receptor signaling pathway
regulation of T cell receptor signaling pathway
positive regulation of T cell activation
positive regulation of NF-kappaB transcription factor activity
nuclear export
protein oligomerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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