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Immunogen sequence: QGQAFHLDRR NSPPNSLTPC LKIRNMFDPV MEIGDQWHLA IQEAILEKCS DNDGIVHIAV DKNSREGCVY VKCLSPEYAG KAFKALHGSW FDGKLVTVKY LRLDRYHHRF PQALTSNTPL KPSNKHMNSM SHLRLRT
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Inner nuclear membrane protein Man1; integral inner nuclear membrane protein; LEM domain-containing protein 3
基因别名: LEMD3; MAN1
UniProt ID: (Human) Q9Y2U8
Entrez Gene ID: (Human) 23592