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产品信息
MA5-17116
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5B7
抗原
Purified recombinant fragment of human MAP2 (amino acids: 24-123) expressed in E. Coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2538587
产品详细信息
MA5-17116 targets MAP2 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17116 immunogen is purified recombinant fragment of human MAP2 (amino acids: 24-123) expressed in E. Coli.
MA5-17116 detects MAP2 which has a predicted molecular weight of approximately 199kDa.
靶标信息
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer's Disease (AD).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AC091465.1; DKFZp686I2148; MAP 2; MAP-2; map-2a; map2ab; Microtubule-associated protein 2; OTTHUMP00000163916; OTTHUMP00000208143
基因别名: MAP2; MAP2A; MAP2B; MAP2C
UniProt ID: (Human) P11137
Entrez Gene ID: (Human) 4133
