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Peptide sequence: TSESVGEGHP DKICDQISDA VLDAHLKQDP NAKVACETVC KTGMVLLCGE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
MAT1A catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AdoMet synthase 1; adoMet synthetase 1; MAT 1; MAT-I/III; Methionine adenosyltransferase 1; methionine adenosyltransferase I, alpha; Methionine adenosyltransferase I/III; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthetase isoform type-1
Gene Aliases: AMS1; MAT; MAT1A; MATA1; SAMS; SAMS1
UniProt ID: (Human) Q00266
Entrez Gene ID: (Human) 4143
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