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MAT1A Antibody (712035) in WB
Western blot analysis was performed on Tissue extracts (30 µg lysate) of Mouse liver (Lane 1), Mouse kidney (Lane 2) and Rat kidney (Lane 3). The blots were probed with Anti-MAT1A Recombinant Rabbit Superclonal™ Antibody (Product # 712035,1:200 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.25 µg/mL, 1:4000 dilution). A 43 kDa band corresponding to MAT1A was observed in the relevant tissue tested.
Product Details
712035
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Clone
7HCLC
Immunogen
Protein corresponding to human MAT1A [aa16-aa395]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2734814
Product Specific Information
This antibody is predicted to react with Monkey, Bovine, Rat.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
Target Information
MAT1A catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AdoMet synthase 1; adoMet synthetase 1; MAT 1; MAT-I/III; Methionine adenosyltransferase 1; methionine adenosyltransferase I, alpha; Methionine adenosyltransferase I/III; S-adenosylmethionine synthase isoform type-1; S-adenosylmethionine synthetase isoform type-1
Gene Aliases: AdoMet; AI046368; Ams; AMS1; MAT; MAT1A; MATA1; SAMS; SAMS1
UniProt ID: (Human) Q00266, (Mouse) Q91X83
Entrez Gene ID: (Human) 4143, (Mouse) 11720
methionine adenosyltransferase activity
ATP binding
metal ion binding
selenomethionine adenosyltransferase activity
nucleotide binding
magnesium ion binding
amino acid binding
transferase activity
identical protein binding
protein homodimerization activity
ADP binding
protein dimerization activity
nucleotidyltransferase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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