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产品信息
PA5-18325
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (STSHLAVCEFPI) corresponding to the C-terminus amino acids of MBL2 (aa 237-248).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10981236
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
靶标信息
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Collectin-1; Collectin1; mannan-binding lectin; Mannan-binding protein; Mannose-binding lectin; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); Mannose-binding protein C; MBP-C; MBP1; MBPC; MGC116832; MGC116833
基因别名: COLEC1; HSMBPC; MBL; MBL2; MBL2D; MBP; MBP-C; MBP1; MBPD
UniProt ID: (Human) P11226
Entrez Gene ID: (Human) 4153
complement activation, lectin pathway
proteolysis
acute-phase response
complement activation
complement activation, classical pathway
response to oxidative stress
opsonization
defense response to bacterium
negative regulation of growth of symbiont in host
innate immune response
negative regulation of viral process
positive regulation of phagocytosis
defense response to Gram-positive bacterium
killing by host of symbiont cells
