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产品信息
H00008720-M07
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2E6
抗原
MBTPS1 (NP_957720.1, 246 a.a. approximately 355 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: GLGHGTFVAG VIASMRECQG FAPDAELHIF RVFTNNQVSY TSWFLDAFNY AILKKIDVLN LSIGGPDFMD HPFVDKVWEL TANNVIMVSA IGNDGPLYGT LNNPADQMDV
靶标信息
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endopeptidase S1P; membrane-bound transcription factor peptidase, site 1; Membrane-bound transcription factor site-1 protease; proprotein convertase subtilisin/kexin type 8; site-1 protease; SKI-1; subtilisin kexin isozyme 1; subtilisin/kexin isozyme-1; Subtilisin/kexin-isozyme 1
基因别名: KIAA0091; MBTPS1; PCSK8; S1P; SKI-1; SKI1
UniProt ID: (Human) Q14703
Entrez Gene ID: (Human) 8720
