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Immunogen sequence: RNKHEGIADK LLAKIAKLQR RIKTVLLFQR NCLKPNMLSS NGASKVANSE AMILDKNLES VNSPIEKSSV NYEPSNPSEK GSKKINLSSD QNKSVSESNN DD
Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 52%.
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (Probable). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activating transcription factor 7-interacting protein 2; ATF7-interacting protein 2; MBD1-containing chromatin associated factor 2; MBD1-containing chromatin-associated factor 2
基因别名: ATF7IP2; MCAF2
UniProt ID: (Human) Q5U623
Entrez Gene ID: (Human) 80063