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MCAK Antibody (PA5-27833) in ICC/IF
MCAK Polyclonal Antibody detects MCAK protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MCAK protein stained by MCAK Polyclonal Antibody (Product # PA5-27833) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-27833
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 9 and 287 of Human MCAK
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545309
产品详细信息
Recommended positive controls: K562.
Predicted reactivity: Mouse (80%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Kinesin-like protein 6; Kinesin-like protein KIF2C; MCAK; Mitotic centromere-associated kinesin; RP11-269F19.1; testis tissue sperm-binding protein Li 68n
基因别名: CT139; KIF2C; KNSL6; MCAK
UniProt ID: (Human) Q99661
Entrez Gene ID: (Human) 11004
retrograde vesicle-mediated transport, Golgi to ER
microtubule-based movement
microtubule depolymerization
sister chromatid cohesion
mitotic nuclear division
mitotic metaphase plate congression
cell proliferation
antigen processing and presentation of exogenous peptide antigen via MHC class II
establishment or maintenance of microtubule cytoskeleton polarity
cell division
regulation of chromosome segregation
