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产品信息
MA5-34701
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JB99-35
抗原
Synthetic peptide within Human MCM3 aa 1-50
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles, store in dark
运输条件
Wet ice
RRID
AB_2848609
产品详细信息
Positive Control: Mouse thymus tissue lysate, NIH-3T3, Hela, 293T, HepG2, SH-SY-5Y, rat testis tissue, human tonsil tissue, human placenta tissue, mouse small intestine tissue, K562.
靶标信息
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cervical cancer proto-oncogene 5; DNA polymerase alpha holoenzyme-associated protein P1; DNA replication factor MCM3; DNA replication licensing factor MCM3; hRlf beta subunit; MCM3 minichromosome maintenance deficient 3; MGC1157; minichromosome maintenance deficient 3; P1-MCM3; p102; replication licensing factor, beta subunit; RLF subunit beta; RP1-108C2.3
基因别名: HCC5; MCM3; P1-MCM3; P1.h; RLFB
UniProt ID: (Human) P25205
Entrez Gene ID: (Human) 4172
