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MDC1 Antibody (MA5-27650) in ICC/IF
Immunofluorescent analysis of MDC1 in mouse fibroblast cell line (NIH 3T3). Sample was fixed with 4% formaldehyde (15 min at RT), incubated with MDC1 monoclonal antibody (Product # MA5-27650) using a dilution of 1:100 (1 hour at RT), and followed by Goat Anti-Mouse Alexa Fluor 488 and DAPI secondary antibody at a dilution of 1:100 (60 min at RT) and 1:5000 (5 min at RT). Magnification: 60x.
产品信息
MA5-27650
产品规格
种属反应
Bovine,
Human,
Mouse,
Non-human primate
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
P2B11
抗原
GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2735265
产品详细信息
0.5 µg/mL of MA5-27650 was sufficient for detection of MDC1 in 10 µg of HeLa cell lysate by ECL immunoblot analysis.|Detects approximately 184kDa. This antibody recognizes MDC1 at and around the N-terminus.
靶标信息
MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; mediation of DNA damage checkpoint 1; Mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; Nuclear factor with BRCT domains 1
基因别名: 6820401C03; AA413496; KIAA0170; MDC1; mKIAA0170; NFBD1
UniProt ID: (Human) Q14676, (Mouse) Q5PSV9
Entrez Gene ID: (Human) 9656, (Mouse) 240087
