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MDH1 Antibody (PA5-96721) in WB
Western blot analysis of MDH1 in extracts of various cell lines. Samples were incubated with MDH1 Polyclonal antibody (Product # PA5-96721) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-96721
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human MDH1 (NP_0059081)
偶联物
形式
Liquid
浓度
3.31 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808523
产品详细信息
Immunogen sequence: MSEPIRVLVT GAAGQIAYSL LYSIGNGSVF GKDQPIILVL LDITPMMGVL DGVLMELQDC ALPLLKDVIA TDKEDVAFKD LDVAILVGSM PRREGMERKD LLKANVKIFK SQGAALDKYA KKSVKVIVVG NPANTNCLTA SKSAPSIPKE NFSCLTRLDH NRAKAQIALK LGVTANDVKN VIIWGNHSST QYPDVNHAKV KLQGKEVGVY EALKDDSWLK GEFVTTVQQR GAAVIKARKL SSAMSAAKAI CDHVRDIWFG TPEGEFVSMG VISDGNSYGV PDDLLYSFPV VIKNKTWKFV EGLPINDFSR EKMDLTAKEL TEEKESAFEF LSSA; Positive Samples: HepG2, THP-1, HeLa, Jurkat, Mouse liver, Mouse kidney, Mouse heart, Mouse eye, Rat kidney; Cellular Location: Cytoplasm
靶标信息
MDH1 is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Aromatic alpha-keto acid reductase; Cytosolic malate dehydrogenase; diiodophenylpyruvate reductase; epididymis secretory protein Li 32; KAR; malate dehydrogenase 1, NAD (soluble); Malate dehydrogenase, cytoplasmic; malate dehydrogenase, soluble; Malate dehydrogenase-like enzyme; soluble malate dehydrogenase
基因别名: B230377B03Rik; D17921; HEL-S-32; Mdh; MDH-s; MDH1; MDHA; Mdhl; MDL1; MGC:1375; Mor-2; MOR2
UniProt ID: (Human) P40925, (Mouse) P14152, (Rat) O88989
Entrez Gene ID: (Human) 4190, (Mouse) 17449, (Rat) 24551
malic enzyme activity
protein binding
L-malate dehydrogenase activity
diiodophenylpyruvate reductase activity
NAD binding
catalytic activity
oxidoreductase activity
malate dehydrogenase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
positive regulation of defense response to virus by host
gluconeogenesis
tricarboxylic acid cycle
oxaloacetate metabolic process
malate metabolic process
NADH metabolic process
mitophagy in response to mitochondrial depolarization
xenophagy
carbohydrate metabolic process
NAD metabolic process
carboxylic acid metabolic process
oxidation-reduction process
cellular carbohydrate metabolic process
