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产品信息
PA5-109952
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human MED25 (NP_112235.2).
偶联物
形式
Liquid
浓度
1.64 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855363
产品详细信息
Immunogen sequence: PYFEGLRKHY LLPAIEYFNG GPPAETDFGG DYGGTQYSLV VFNTVDCAPE SYVQCHAPTS SAYEFVTWLD GIKFMGGGGE SCSLIAEGLS TALQLFDDFK KMREQIGQTH RVCLLICNSP PYLLPAVEST TYSGCTTENL VQQIGERGIH FSIVSPRKLP ALRLLFEKAA P
靶标信息
This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Activator interaction domain-containing protein 1; Activator-recruited cofactor 92 kDa component; ARC/mediator transcriptional coactivator subunit; ARC92; DKFZp434K0512; Mediator complex subunit 25; Mediator of RNA polymerase II transcription subunit 25; mediator of RNA polymerase II transcription, subunit 25 homolog; mediator of RNA polymerase II transcription, subunit 9 homolog; MGC70671; mMED25; p78; prostate-derived protein 78 kDa
基因别名: 2610034E13Rik; 2610529E18Rik; ACID1; ARC92; BVSYS; CMT2B2; ESTM2; MED25; P78; PTOV2; RGD1305137; TCBAP0758
UniProt ID: (Human) Q71SY5, (Mouse) Q8VCB2
Entrez Gene ID: (Human) 81857, (Mouse) 75613, (Rat) 292889
negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
positive regulation of chromatin binding
positive regulation of transcription from RNA polymerase II promoter
negative regulation of fibroblast proliferation
positive regulation of cell cycle arrest
positive regulation of mediator complex assembly
transcription, DNA-templated
regulation of transcription, DNA-templated
biological_process
