Abnova

MED4 Monoclonal Antibody (2B10)

图: 1 / 1

MED4 Antibody (H00029079-M01) in WB

Western Blot analysis of MED4 expression in transfected 293T cell line by MED4 monoclonal antibody (M01), clone 2B10. Lane 1: MED4 transfected lysate(29.7 KDa). Lane 2: Non-transfected lysate. .

Product Image Gallery

产品信息

H00029079-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

免疫细胞化学 (ICC/IF)

10-100 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

2B10

抗原

MED4 (AAH05189, 1 a.a. approximately 270 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Transfected lysate).

Immunogen sequence: MAASSSGEKE KERLGGGLGV AGGNSTRERL LSALEDLEVL SRELIEMLAI SRNQKLLQAG EENQVLELLI HRDGEFQELM KLALNQGKIH HEMQVLEKEV EKRDGDIQQL QKQLKEAEQI LATAVYQAKE KLKSIEKARK GAISSEEIIK YAHRISASNA VCAPLTWVPG DPRRPYPTDL EMRSGLLGQM NNPSTNGVNG HLPGDALAAG RLPDVLAPQY PWQSNDMSMN MLPPNHSSDF LLEPPGHNKE DEDDVEIMST DSSSSSSESD

靶标信息

The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for activation of polymerase II transcribed genes. MED4 appears to be a core Mediator subunit and is found in nearly all Mediator preparations (Sato et al., 2004).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Activator-recruited cofactor 36 kDa component; ARC36; DRIP36; FLJ10956; Mediator complex subunit 4; Mediator of RNA polymerase II transcription subunit 4; mediator, 34-kD subunit, homolog; RP11-90M2.2; TRAP/SMCC/PC2 subunit p36; TRAP/SMCC/PC2 subunit p36 subunit; vitamin D receptor-interacting protein, 36-kD; Vitamin D3 receptor-interacting protein complex 36 kDa component

查看更多收起

基因别名: ARC36; DRIP36; HSPC126; MED4; TRAP36; VDRIP

查看更多收起

UniProt ID: (Human) Q9NPJ6

查看更多收起

Entrez Gene ID: (Human) 29079

查看更多收起

功能

RNA polymerase II transcription cofactor activity transcription cofactor activity receptor activity protein binding ligand-dependent nuclear receptor transcription coactivator activity vitamin D receptor binding thyroid hormone receptor binding general transcription factor

参与通路

regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter transcription initiation from RNA polymerase II promoter intracellular steroid hormone receptor signaling pathway androgen receptor signaling pathway positive regulation of transcription, DNA-templated