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产品信息
MEDEA-101AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Fruit fly
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 150-250 on Drosophila melanogaster Medea protein.
偶联物
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Medea is a gene from the fruit fly Drosophila melanogaster that was one of the first two Smad genes discovered. For both genes, the maternal effect lethality was the basis for selection of their names. Both Medea and Mothers against dpp were identified in a genetic screen for maternal effect mutations that caused lethality of heterozygous decapentaplegic progeny.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CG1775; CG1775-PA; CG1775-PB; CG1775-PC; class II Smad; LD22279p; lethal(3)SG36; lethal(3)SG70; Med; Med-PA; Med-PB; Med-PC; Medea; media; Mothers against decapentaplegic homolog
基因别名: anon-EST:Posey121; CG1775; Dmel\CG1775; Dmel_CG1775; dSmad4; E(zen)3; l(3)11m-254; l(3)12m-137; l(3)SG36; l(3)SG70; l(3)XIIm137; MED; medea; SMAD4
Entrez Gene ID: (Fruit fly) 43725
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
transcription factor binding
ubiquitin protein ligase binding
I-SMAD binding
DNA-binding transcription factor
gene-specific transcriptional regulator
negative regulation of transcription from RNA polymerase II promoter
compound eye morphogenesis
transforming growth factor beta receptor signaling pathway
imaginal disc-derived wing morphogenesis
imaginal disc-derived leg morphogenesis
heart development
anatomical structure morphogenesis
dorsal/ventral axis specification
dorsal/ventral pattern formation
cell differentiation
BMP signaling pathway
ovarian follicle cell development
germ-line stem cell population maintenance
retinal ganglion cell axon guidance
activin receptor signaling pathway
somatic stem cell population maintenance
germ-line stem cell division
negative regulation of salivary gland boundary specification
positive regulation of synaptic growth at neuromuscular junction
positive regulation of transcription from RNA polymerase II promoter
neuron development
SMAD protein signal transduction
