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产品信息
PA5-27344
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat,
Zebrafish
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 165 of Human MEF2A
偶联物
形式
Liquid
浓度
0.77 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2544820
产品详细信息
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (100%), Rat (100%), Pig (99%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The proteins belonging to structural maintenance of chromosomes (SMC) family play critical roles in chromosome structural changes. SMC proteins are involved in the proper condensation and segregation of mitotic chromosomes. Four human SMC proteins that form two distinct heterodimeric complexes in the cell, the human chromosome-associated protein (hCAP)-C and hCAP-E protein complex (hCAP-C/hCAP-E), and the human SMC1 (hSMC1) and hSMC3 protein complex (hSMC1/hSMC3) have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A); Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1; transcription factor MEF2A
基因别名: A430079H05Rik; ADCAD1; etID309779.18; MEF2; MEF2A; RSRFC4; RSRFC9; wu:fd19d02
UniProt ID: (Human) Q02078, (Mouse) Q60929, (Rat) Q2MJT0
Entrez Gene ID: (Human) 4205, (Mouse) 17258, (Rat) 309957, (Zebrafish) 30564
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
RNA polymerase II transcription coactivator activity
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein kinase binding
activating transcription factor binding
histone acetyltransferase binding
histone deacetylase binding
sequence-specific DNA binding
SMAD binding
protein heterodimerization activity
DNA binding
protein dimerization activity
transcription regulatory region sequence-specific DNA binding
transcription factor binding
MADS box transcription factor
mitochondrial genome maintenance
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
transcription, DNA-templated
transcription from RNA polymerase II promoter
apoptotic process
heart development
muscle organ development
positive regulation of cardiac muscle hypertrophy
positive regulation of transcription from RNA polymerase II promoter
mitochondrion distribution
dendrite morphogenesis
positive regulation of muscle cell differentiation
ventricular cardiac myofibril assembly
cardiac conduction
ERK5 cascade
cellular response to calcium ion
regulation of transcription, DNA-templated
multicellular organism development
nervous system development
cell differentiation
positive regulation of transcription, DNA-templated
cellular response to glucose stimulus
somitogenesis
positive regulation of gene expression
myofibril assembly
