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This target displays homology in the following species: Cow: 83%; Dog: 91%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 92%
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Meiosis-specific with OB domain-containing protein
基因别名: C16orf73; gs129; MEIOB
UniProt ID: (Human) Q96RY0
Entrez Gene ID: (Human) 254528