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MEKK2 Antibody (PA5-95003) in WB
Western blot analysis of MEKK2 in, Lane 1: rat kidney tissue lysates Lane 2: rat brain tissue lysates Lane 3: rat heart tissue lysates Lane 4: rat C6 whole cell lysates Lane 5: mouse kidney tissue lysates Lane 6: mouse brain tissue lysates Lane 7: mouse heart tissue lysates Lane 8: mouse Neuro-2a whole cell lysates Lane 9: mouse NIH/3T3 whole cell lysates . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50 µg of sample under reduc... View More
产品信息
PA5-95003
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human MEKK2 (606-619aa SADELLRHMFVHYH).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2806809
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
靶标信息
MAP3K2 (MEKK2) is a serine/threonine kinase that activates kinases involved in the MAP kinase signaling pathway. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2.7.11.25; MAP/ERK kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; mitogen activated protein kinase kinase kinase 2; Mitogen-activated protein kinase kinase kinase 2; protein kinase MEKK2b
基因别名: 9630061B06Rik; AI585793; MAP3K2; MAPKKK2; MEKK2; MEKK2B
UniProt ID: (Human) Q9Y2U5
Entrez Gene ID: (Human) 10746, (Rat) 171492, (Mouse) 26405
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
metal ion binding
MAP kinase kinase activity
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
