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Positive Control: Rat kidney tissue lysates, rat kidney tissue.
Subcellular Location: Nucleus.
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Growth arrest-specific homeobox; Homeobox protein MOX-2; mesenchyme homeo box 2 (growth arrest-specific homeo box); Mesenchyme homeobox 2
基因别名: GAX; MEOX2; Mox-2; MOX2
UniProt ID: (Human) P50222, (Rat) P39020
Entrez Gene ID: (Human) 4223, (Rat) 29279