Invitrogen

MESP1 Polyclonal Antibody

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MESP1 Antibody (PA5-87675) in WB

Western blot analysis of MESP1 in extracts of various cell lines. Samples were incubated with MESP1 Polyclonal antibody (Product # PA5-87675) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

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产品信息

PA5-87675

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200-1:1,000

免疫组化（石蜡） (IHC (P))

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 149-268 of human MESP1 (NP_0611401)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.54 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2804339

产品详细信息

Immunogen sequence: RRCRQRGDAG SPRGCPLCPD DCPAQMQTRT QAEGQGQGRG LGLVSAVRAG ASWGSPPACP GARAAPEPRD PPALFAEAAC PEGQAMEPSP PSPLLPGDVL ALLETWMPLS PLEWLPEEPK; Positive Samples: A-549, HeLa, THP-1, Mouse heart, Rat heart; Cellular Location: Nucleus

靶标信息

Mesp1 (mesoderm posterior 1) is a basic helix-loop-helix-type transcription factor, which along with its related proteins, has an essential role in both segmentation and rostro-caudal patterning of somites in the anterior pre-somitic mesoderm. Mesp1 is expressed in many of the precursors of the cardiovascular system and is known to play a role in the process of cardiac morphogenesis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: bHLHc5; Class C basic helix-loop-helix protein 5; mesoderm posterior 1 homolog; mesoderm posterior basic helix-loop-helix transcription factor 1; Mesoderm posterior protein 1; MGC10676

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基因别名: BHLHC5; MESP1

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UniProt ID: (Human) Q9BRJ9, (Mouse) P97309

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Entrez Gene ID: (Human) 55897, (Rat) 308766, (Mouse) 17292

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding enhancer binding transcription regulatory region DNA binding protein dimerization activity DNA binding

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