Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-96971
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-244 of human METTL7A (NP_0547523)
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808773
产品详细信息
Immunogen sequence: WICKKWFPYF LVRFTVIYNE QMASKKRELF SNLQEFAGPS GKLSLLEVGC GTGANFKFYP PGCRVTCIDP NPNFEKFLIK SIAENRHLQF ERFVVAAGEN MHQVADGSVD VVVCTLVLCS VKNQERILRE VCRVLRPGGA FYFMEHVAAE CSTWNYFWQQ VLDPAWHLLF DGCNLTRESW KALERASFSK LKLQHIQAPL SWELVRPHIY GYAVK; Positive Samples: 22Rv1; Cellular Location: Endoplasmic reticulum, Lipid droplet, Membrane
靶标信息
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: methyltransferase like 7A; methyltransferase like 7A-like; Methyltransferase-like protein 7A; N6-adenosine-methyltransferase TMT1A; Protein AAM-B; Thiol methyltransferase 1A; Thiol S-methyltransferase TMT1A
基因别名: 2210414H16Rik; 3300001H21Rik; AAM-B; METTL7A; PRO0066; RGD1308407; TMT1A; UbiE1; UNQ1902/PRO4348
UniProt ID: (Human) Q9H8H3
Entrez Gene ID: (Human) 25840, (Rat) 315306, (Mouse) 70152
