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产品信息
PA5-142901
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-NRPIHASEPQPHNRT.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933544
产品详细信息
Additional Information: This antibody is expected to recognize isoform 1 (NP_002396.2).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
靶标信息
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.
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生物信息学
蛋白别名: Beta-1,3-N-acetylglucosaminyltransferase manic fringe; EC 2.4.1.222; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
基因别名: MFNG
UniProt ID: (Human) O00587
Entrez Gene ID: (Human) 4242
