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MHC Class I (RT1-A) Antibody (11-0921-82) in Flow
Staining of rat splenocytes with Anti-Rat CD3 PE (Product # 12-0030-82) and 0.5 µg of Mouse IgG1 K Isotype Control FITC (Product # 11-4714-42) (left) or 0.5 µg of Anti-Rat MHC Class I (RT1-A) FITC (right). Total viable cells were used for analysis.
产品信息
11-0921-82
产品规格
种属反应
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
OX18
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.09% sodium azide
保存条件
4° C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2572463
产品详细信息
Description: This OX18 monoclonal antibody recognizes a non-polymorphic determinant of rat MHC Class I, which is also known as RT1-A. Rat MHC Class I is expressed on all nucleated cells and erythrocytes.
The OX18 antibody has been reported to have functional activity.
Applications Reported: This OX18 antibody has been reported for use in flow cytometric analysis.
Applications Tested: This OX18 antibody has been tested by flow cytometric analysis of rat splenocytes. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.
Filtration: 0.2 µm post-manufacturing filtered.
靶标信息
This protein is a non-polymorphic determinant of rat MHC Class I, which is also known as RT1-A. Rat MHC Class I is expressed on all nucleated cells and erythrocytes.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
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生物信息学
蛋白别名: HA11; MHC class I RT1.Aa alpha-chain; Rat class I A; RT1 class I gene (A-1); RT1 class Ia, locus A (A1); RT1 class Ia, locus A1; RT1-A; RT1-AW2
基因别名: RT1.A1(N); RT1A-1
Entrez Gene ID: (Rat) 24973, (Rat) 100188935
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of peptide antigen via MHC class I
T cell tolerance induction
positive regulation of tolerance induction to nonself antigen
immune response
negative regulation of natural killer cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
