Invitrogen

MICAL1 Polyclonal Antibody

View all (34) MICAL1 antibodies
Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-90518

Applications
Tested Dilution
Publications

Western Blot (WB)

1:200-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 718-1067 of human MICAL1 (NP_0736023)
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.75 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806106

Product Specific Information

Immunogen sequence: HRSCFRCHTC EATLWPGGYE QHPGDGHFYC LQHLPQTDHK AEGSDRGPES PELPTPSENS MPPGLSTPTA SQEGAGPVPD PSQPTRRQIR LSSPERQRLS SLNLTPDPEM EPPPKPPRSC SALARHALES SFVGWGLPVQ SPQALVAMEK EEKESPFSSE EEEEDVPLDS DVEQALQTFA KTSGTMNNYP TWRRTLLRRA KEEEMKRFCK AQTIQRRLNE IEAALRELEA EGVKLELALR RQSSSPEQQK KLWVGQLLQL VDKKNSLVAE EAELMITVQE LNLEEKQWQL DQELRGYMNR EENLKTAADR QAEDQVLRKL VDLVNQRDAL IRFQEERRLS ELALGTGAQG; Positive Samples: A-549, HT-29, Raji; Cellular Location: Cytoplasm, cytoskeleton

Target Information

May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: [F-actin]-monooxygenase MICAL1; CasL interacting molecule MICAL; MICAL-1; microtubule associated monoxygenase, calponin and LIM domain containing 1; mMical1; Molecule interacting with CasL protein 1; NEDD9 interacting protein with calponin homology and LIM domains; NEDD9-interacting protein with calponin homology and LIM domains; protein-methionine sulfoxide oxidase MICAL1

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Gene Aliases: MICAL; MICAL-1; MICAL1; NICAL

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UniProt ID: (Human) Q8TDZ2, (Mouse) Q8VDP3

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Entrez Gene ID: (Human) 64780, (Mouse) 171580

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Function(s)
actin binding protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen SH3 domain binding Rab GTPase binding FAD binding monooxygenase activity 3-(3-hydroxyphenyl)propionate hydroxylase activity oxidoreductase activity 4-chlorobenzaldehyde oxidase activity 3,5-xylenol methylhydroxylase activity phenylacetate hydroxylase activity 4-nitrophenol 4-monooxygenase activity dimethyl sulfide monooxygenase activity alpha-pinene monooxygenase [NADH] activity phenanthrene 9,10-monooxygenase activity 1-hydroxy-2-naphthoate hydroxylase activity toluene 4-monooxygenase activity xylene monooxygenase activity dibenzothiophene monooxygenase activity 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity chlorophenol 4-monooxygenase activity carbon disulfide oxygenase activity toluene 2-monooxygenase activity 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity phenanthrene 1,2-monooxygenase activity tetrahydrofuran hydroxylase activity styrene monooxygenase activity toluene-4-sulfonate monooxygenase activity toluene-sulfonate methyl-monooxygenase activity 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity 2-hydroxy-phenylacetate hydroxylase activity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity phenanthrene 3,4-monooxygenase activity toluene 3-monooxygenase activity 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity limonene monooxygenase activity 2-methylnaphthalene hydroxylase activity 1-methylnaphthalene hydroxylase activity bisphenol A hydroxylase A activity salicylate 5-hydroxylase activity isobutylamine N-hydroxylase activity branched-chain dodecylbenzene sulfonate monooxygenase activity 3-HSA hydroxylase activity 4-hydroxypyridine-3-hydroxylase activity 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity 6-hydroxynicotinate 3-monooxygenase activity metal ion binding tocotrienol omega-hydroxylase activity thalianol hydroxylase activity actin or actin-binding cytoskeletal protein
Process(es)
negative regulation of protein phosphorylation cytoskeleton organization signal transduction sulfur oxidation actin filament depolymerization negative regulation of cysteine-type endopeptidase activity involved in apoptotic process oxidation-reduction process negative regulation of apoptotic process
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