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产品信息
PA5-59178
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human MICALCL. Recombinant protein control fragment (Product #RP-97334).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2643958
产品详细信息
Immunogen sequence: IRRSLEPLLS NSEGGKKAWA KQESKTLPTQ ACTRSFSLRK TNSNKDGDQH SPGRNQSSAF SPPDPALRTH SLPNRPSKVF PALRSPPCSK IEDVPTLL
Highest antigen sequence identity to the following orthologs: Mouse - 49%, Rat - 50%.
靶标信息
MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. There are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2. MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain and a Lin11, Isl-1 and Mec-3 (LIM) domain. It has been demonstrated that MICAL2 could regulate actin stress fibers and is required for normal actin organization. In addition, MICAL2-PV, a novel splicing variants of MICAL2, has been reported to be involved in cancer progression of prostate cancer.
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生物信息学
蛋白别名: [F-actin]-monooxygenase MICAL2; flavoprotein oxidoreductase MICAL2; MICAL C-terminal-like protein; MICAL-2; Mical-cL; microtubule associated monoxygenase, calponin and LIM domain containing 2; Molecule interacting with CasL protein 2
基因别名: KIAA0750; MICAL-2; MICAL2; MICAL2PV1; MICAL2PV2; MICALCL
UniProt ID: (Human) Q7Z3A8
Entrez Gene ID: (Human) 9645
