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MICALL2 Antibody (PA5-24826) in IHC (P)
Immunohistochemistry analysis of MICALL2 in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with MICALL2 polyclonal antibody (Product # PA5-24826) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-24826
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 841-870 amino acids from the C-terminal region of human MILK2
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2542326
靶标信息
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Junctional Rab13-binding protein; MICAL-L2; MICAL-like 2; MICAL-like protein 2; milk2; Molecule interacting with CasL-like 2
基因别名: JRAB; MICAL-L2; MICALL2
UniProt ID: (Human) Q8IY33
Entrez Gene ID: (Human) 79778
