Search Thermo Fisher Scientific
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: matrix metallo protease; matrix metallopeptidase 11 (stromelysin 3); Matrix metalloproteinase 11 (stromelysin 3); Matrix metalloproteinase-11; MMP; MMP-11; MMPs; SL-3; stromelysin III; Stromelysin-3
基因别名: MMP-11; MMP11; SL-3; ST3; STMY3
UniProt ID: (Human) P24347, (Mouse) Q02853, (Rat) Q499S5
Entrez Gene ID: (Human) 4320, (Mouse) 17385, (Rat) 25481