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产品信息
PA5-28076
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Mouse,
Rat
已发表种属
Bovine,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 205 and 267 of Human MMP7
偶联物
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545552
产品详细信息
Recommended positive controls: A549.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: HGNC:7174; Matrilysin; matrilysin, uterine; Matrin; matrix metallo protease; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); Matrix metalloproteinase-7; MMP; MMP 7; MMP-7; MMPs; PUMP 1; Pump 1 protease; Pump-1 protease; uterine matrilysin; Uterine metalloproteinase
基因别名: MAT; MMP-7; MMP7; MPMM; MPSL1; PUMP-1; PUMP1
UniProt ID: (Human) P09237, (Rat) P50280
Entrez Gene ID: (Human) 4316, (Bovine) 286794, (Rat) 25335, (Mouse) 17393
proteolysis
aging
extracellular matrix disassembly
collagen catabolic process
response to nutrient levels
estrous cycle
maternal process involved in female pregnancy
cellular response to mechanical stimulus
antibacterial peptide secretion
antibacterial peptide biosynthetic process
regulation of cell proliferation
response to drug
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
