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Recommended positive controls: A549, HeLa, HCT116, mouse brain.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (82%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression and signaling. The MAGUK family is divided into four subfamilies: DLG-like, ZO1-like, p55-like and LIN2-like. MPP2 (membrane protein, palmitoylated 2), also known as MAGUK p55 subfamily member 2, discs large homolog 2 or DLG2, is a 576 amino acid protein belonging to the MAGUK family that exists as three alternatively spliced isoforms. MPP2 contains one guanylate kinase-like domain, a PDZ (DHR) domain, two L27 domains and a single SH3 domain. The gene encoding MPP2 maps to the same segment of human chromosome 17 as MPP3, with whom MMP2 likely shares similar function and common structural organization.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Discs large homolog 2; discs large, homolog 2; MAGUK p55 subfamily member 2; membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2); p55 subfamily member of MAGUK family; Protein MPP2
基因别名: D11Bwg0652e; DLG2; Dlgh2; MPP2; Pals4
UniProt ID: (Human) Q14168, (Mouse) Q9WV34
Entrez Gene ID: (Human) 4355, (Mouse) 50997