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Immunogen sequence: KDAYELEVLL RVKESEIQYL KQEISSLKDE LQTALRDKKY ASDKYKDIYT ELSIAKAKAD CDISRLKEQL KAATEALGEK SPDSATVSGY DIMKSKSNPD FLKKDRSCVT RQL
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: M-RIP; Myosin phosphatase Rho-interacting protein; myosin phosphatase-Rho interacting protein; p116 Rho interacting protein; p116Rip; Rho interacting protein 3; Rho-interacting protein 3; Rho-interacting protein 3 (p116RIP) (RIP3); RIP3
基因别名: 9530046C02; AA536749; AI647711; C76423; KIAA0864; M-RIP; mKIAA0864; MPRIP; MRIP; p116Rip; RHOIP3; RIP3
UniProt ID: (Human) Q6WCQ1, (Mouse) P97434, (Rat) Q9ERE6
Entrez Gene ID: (Human) 23164, (Mouse) 26936, (Rat) 116504