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产品信息
PA5-18195
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (APKQDPKPKFQEG) corresponding to the N-terminus amino acids of MORF4L1 (aa 2-14).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10990049
产品详细信息
This antibody is predicted to react with bovine, human, porcine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
靶标信息
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
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生物信息学
蛋白别名: Esa1p-associated factor 3 homolog; MGC10631; MORF-related gene 15 protein; MORF-related gene on chromosome 15; Mortality factor 4-like protein 1; Protein MSL3-1; testis expressed gene 189; Testis-expressed gene 189 protein; Transcription factor-like protein MRG15
基因别名: Eaf3; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MORF4L1; MORFRG15; MRG15; PP368; S863-6; TEG-189; Tex189
UniProt ID: (Human) Q9UBU8, (Rat) Q6AYU1, (Mouse) P60762
Entrez Gene ID: (Human) 10933, (Rat) 300891, (Mouse) 21761
double-strand break repair via homologous recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
cell proliferation
histone deacetylation
regulation of growth
histone H4 acetylation
histone H2A acetylation
chromatin remodeling
chromatin silencing
chromatin modification
DNA repair
DNA recombination
cellular response to DNA damage stimulus
