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MRP4 Antibody (MA1-35681) in WB
Cancers 2021 -
Figure 5 Western blot analysis of p-CREB, CREB, p-EGFR, EGFR, p-ERK1/2, ERK1, ERK2, EP4, and MRP4 in OVCAR-5 cells. Cells were treated with the indicated agents for 24 h, then light-activated (0.1 J/cm 2 , 10 mW/cm 2 ) or maintained in dark conditions. After 24 h, cells were agonized with EGF (50 ng/mL) and PGE 2 (1 uM) for 10 min, then whole extracts were collected and analyzed using Western blot. ( A ) Re... View More
产品信息
MA1-35681
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
M4I-10
抗原
Maltose Binding Protein and aa 372-431 of MRP4
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
PBS with 0.1% BSA
内含物
0.02% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_1069902
产品详细信息
MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-10 Mab also reacts with the mouse orthologue of the transporter molecule (Mrp4).
靶标信息
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ATP-binding cassette sub-family C member 4; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); EST170205; MOAT-B; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; Multidrug resistance-associated protein 4; RP11-74A12.1
基因别名: ABCC4; D630049P08Rik; MOAT-B; MOATB; MRP4
UniProt ID: (Human) O15439, (Mouse) E9Q236
Entrez Gene ID: (Human) 10257, (Mouse) 239273
