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产品信息
PA5-54674
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644120
产品详细信息
Immunogen sequence: PCLGLRAAAF RLARRQVPCV CAVRHMRSSG HQRCEALAGA PLDNAPKEYP PKIQQLVQDI ASLTLLEISD LNELLKKTLK IQDVGLVPMG G
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 81%.
靶标信息
MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein that is involved in protein synthesis within the mitochondrion. MRPL12 is enhanced in growth-stimulated cells as a result of transcriptional activation, suggesting that it may function as a translational regulator of mitochondrial mRNAs. Impairment of MRPL12 leads to reduction in cell growth rate, decreased mitochondrial ATP production and abolition of mitochondrial oxidative phosphorylation. MRPL12 is cleaved during its translocation across the mitochondrial membrane and it exists as dimers that bind the large ribosomal subunit. MRPL12 is 198 amino acids in length, belongs to the ribosomal protein L12P family and is highly expressed in the colon.
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生物信息学
蛋白别名: 39S ribosomal protein L12, mitochondrial; 5c5-2; FLJ60124; L12mt; Large ribosomal subunit protein bL12m; MGC8610; MRP-L12
基因别名: 5c5-2; L12mt; MRP-L31/34; MRPL12; MRPL7; MRPL7/L12; RPML12
UniProt ID: (Human) P52815
Entrez Gene ID: (Human) 6182
